705993

Sigma-Aldrich

3--25-羟基维生素 D3

98% (CP)

Empirical Formula (Hill Notation):
C27H44O2
CAS号:
分子量:
400.64
MDL编号:
PubChem化学物质编号:
NACRES:
NA.24

质量水平

200

测定

98% (CP)

形式

powder

应用

mass spectrometry (MS): suitable

颜色

white to off-white

质量偏移

M+3

储存温度

−20°C

SMILES string

C[C@@]12[C@](CC[C@]2([H])[C@@H](CCCC(C)(O)C)C)([H])/C(CCC1)=C/C=C3C[C@H](O)CCC/3=C

InChI

1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23-,24-,25+,27-/m1/s1

InChI key

JWUBBDSIWDLEOM-UEGFJKGBSA-N

相关类别

应用

3-表-25-羟基维生D3又称为3-epi-25(OH)D3。它是维生素D3在肝脏中形成的代谢物。3-epi-25(OH)D3可作为生物标记物测定维生素D的体内状态。还可作为分析标准品,测定人血清中的3-epi-25(OH)D3分子浓度。

包装

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象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

RIDADR

UN 2811 6.1 / PGII

WGK Germany

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

分析证书

原产地证书 (CofO)

Yosef Dror et al.
The Journal of clinical endocrinology and metabolism, 98(5), 2160-2167 (2013-03-28)
Low serum calcidiol has been associated with multiple comorbidities and mortality but no "safe" range has been found for the upper concentration. We aim to establish the upper threshold of serum calcidiol, beyond which there is an increased risk for...
3-epi-25 hydroxyvitamin D concentrations are not correlated with age in a cohort of infants and adults
Strathmann FG, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 413(1-2), 203-206 (2012)
Alex Aregbesola et al.
Journal of epidemiology and community health, 67(6), 533-536 (2013-04-19)
Vitamin D has been suggested to have a role in infection defence and on the immune system. We therefore investigated the effect of serum 25-hydroxyvitamin D₃ (25(OH)D₃) on the risk of incident hospitalised pneumonia in an ageing general population in...
P V Pradeep et al.
Journal of postgraduate medicine, 59(1), 4-8 (2013-03-26)
No single factor can predict the occurrence of post total thyroidectomy (TT) hypocalcemia. This study was conducted to look at various factors usually implicated in post TT clinically significant hypocalcemia (CSH) and to develop a scoring system using a combination...
Andrzej Slominski et al.
The Journal of clinical endocrinology and metabolism, 98(2), E298-E303 (2013-01-09)
There is no effective treatment for systemic sclerosis and related fibrosing diseases. Recently the action of CYP11A1 on vitamin D(3) was shown to produce biologically active 20S-hydroxyvitamin D [20(OH)D(3)] and 20,23(OH)(2)D(3), 20,22(OH)(2)D(3), and 17,20,23(OH)(3)D(3). Because 20(OH)D(3) is noncalcemic (nontoxic) in...
技术文章
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Using HybridSPE-Phospholipid, Ascentis Express, and Other LC-MS Workflow Components
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This application shows an Ascentis Express F5 provided rapid resolution of the isobaric vitamin D metabolites. MS detection provides the necessary secondary resolution.
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The metabolic role and health implications of the various vitamin D isoforms are of current clinical interest. Therefore, it is important to have an analytical method that will resolve all of the known isoforms with necessary sensitivity and specificity
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