Merck

746223

Sigma-Aldrich

马来酰亚胺-PEG2-琥珀酰亚胺酯

≥95%

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别名:
3-[2-[2-[[3-(2,5-二氢-2,5-二氧代-1H-吡咯-1-基)-1-氧代丙基]氨基]乙氧基]乙氧基]丙酸2,5-二氧代-1-吡咯烷基酯, 马来酰亚胺-PEG2-NHS
Empirical Formula (Hill Notation):
C18H23N3O9
分子量:
425.39
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

检测方案

≥95%

形式

solid

reaction suitability

reaction type: Pegylations
reagent type: cross-linking reagent

mp

92-94 °C

官能团

NHS ester
maleimide

储存温度

−20°C

SMILES string

O=C(N1CCC(NCCOCCOCCC(ON(C(CC2)=O)C2=O)=O)=O)C=CC1=O

InChI

1S/C18H23N3O9/c22-13(5-8-20-14(23)1-2-15(20)24)19-7-10-29-12-11-28-9-6-18(27)30-21-16(25)3-4-17(21)26/h1-2H,3-12H2,(H,19,22)

InChI key

TZPDZOJURBVWHS-UHFFFAOYSA-N

相关类别

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此商品
746193746207746215
form

solid

form

liquid

form

liquid

form

liquid

reaction suitability

reaction type: Pegylations, reagent type: cross-linking reagent

reaction suitability

reaction type: Pegylations, reagent type: cross-linking reagent

reaction suitability

reaction type: Pegylations, reagent type: cross-linking reagent

reaction suitability

reaction type: Pegylations, reagent type: cross-linking reagent

mp

92-94 °C

mp

-

mp

-

mp

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

应用

具有短环氧乙烷间隔基的异双功能交联剂,用于将胺基与含巯基化合物或生物分子的连接。马来酰亚胺官能团将与巯基反应,而琥珀酰亚胺酯基团将与胺反应。间隔基长度为17.6埃。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable


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Sinem K Saka et al.
Nature biotechnology, 37(9), 1080-1090 (2019-08-21)
Spatial mapping of proteins in tissues is hindered by limitations in multiplexing, sensitivity and throughput. Here we report immunostaining with signal amplification by exchange reaction (Immuno-SABER), which achieves highly multiplexed signal amplification via DNA-barcoded antibodies and orthogonal DNA concatemers generated
Sabrina Simoncelli et al.
Cell reports, 33(12), 108523-108523 (2020-12-29)
Elucidating the mechanisms that controlled T cell activation requires visualization of the spatial organization of multiple proteins on the submicron scale. Here, we use stoichiometrically accurate, multiplexed, single-molecule super-resolution microscopy (DNA-PAINT) to image the nanoscale spatial architecture of the primary inhibitor
Thomas Schlichthaerle et al.
Chembiochem : a European journal of chemical biology, 20(8), 1032-1038 (2018-12-28)
Current optical super-resolution implementations are capable of resolving features spaced just a few nanometers apart. However, translating this spatial resolution to cellular targets is limited by the large size of traditionally employed primary and secondary antibody reagents. Recent advancements in
Nirakar Basnet et al.
Nature cell biology, 20(10), 1172-1180 (2018-09-27)
Microtubules are central elements of the eukaryotic cytoskeleton that often function as part of branched networks. Current models for branching include nucleation of new microtubules from severed microtubule seeds or from γ-tubulin recruited to the side of a pre-existing microtubule.
Florian Schueder et al.
Nature communications, 8(1), 2090-2090 (2017-12-14)
Single-molecule localization microscopy (SMLM) can visualize biological targets on the nanoscale, but complex hardware is required to perform SMLM in thick samples. Here, we combine 3D DNA points accumulation for imaging in nanoscale topography (DNA-PAINT) with spinning disk confocal (SDC)

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