Merck
All Photos(1)

761524

Sigma-Aldrich

二苯并环辛炔-N-羟基琥珀酰亚胺酯

for Copper-free Click Chemistry

Synonym(s):
DBCO-NHS酯, DBCO-SE
Empirical Formula (Hill Notation):
C23H18N2O5
Molecular Weight:
402.40
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

质量水平

100

形式

solid

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent

mp

149-157 (decomposition)

储存温度

−20°C

SMILES string

O=C(CCC(ON(C(CC1)=O)C1=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4

InChI

1S/C23H18N2O5/c26-20(13-14-23(29)30-25-21(27)11-12-22(25)28)24-15-18-7-2-1-5-16(18)9-10-17-6-3-4-8-19(17)24/h1-8H,11-15H2

InChI key

XCEBOJWFQSQZKR-UHFFFAOYSA-N

应用

琥珀酰亚胺酯(NHS,胺反应性)官能化的环辛炔衍生物,将环辛炔部分引入含胺的化合物或生物分子中。环辛炔可用于菌株促进的无铜点击化学环加成反应。该二苯并环辛炔可与叠氮官能化化合物或生物分子反应,无需Cu(I)催化剂即可产生稳定的三唑键。

应用包括:
  • 蛋白-肽缀合物
  • 抗体-酶或抗体-药物缀合物
  • 蛋白或肽-寡核苷酸缀合物
  • 表面修饰

包装

1, 5, 50 mg in clear glass bottle

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More Documents

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service