所有图片(1)

808628

Sigma-Aldrich

金纳米颗粒

5 nm diameter, biotin terminated, PEG 5000 coated, OD 50, dispersion in H2O

别名:
生物素金
EC 号:
NACRES:
NA.23

质量水平

100

物料

PEG 5000

形式

dispersion in H2O
nanoparticles

包装

pkg of 0.5 mL

OD

50

直径

5 nm

表面积

61.8 m2/g

pH值(酸碱度)

5-7

密度

1.00 g/cm3

λmax

513-517 nm

官能团

biotin

储存温度

2-8°C

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一般描述

金纳米粒子 PEG 5000 生物素终止。

应用

金纳米颗粒(直径5 nm,生物素封端,PEG 5000包被,OD 50,在H2O中分散)可用作治疗剂,有望用于癌症治疗和COVID-19的治疗。它也可以用于生物传感应用中的病原体检测。AuNP可用于制备SARS-CoV-2偶联物,用于通过侧向流免疫分析(lateral flow immunoassay )技术进行COVID-19检测。
生物素功能化的金纳米颗粒适用于链霉亲和素标记结合物的结合。金纳米颗粒标记通过测定结合后样品吸光度的增加,可直接检测链霉亲和素。最大吸收与金纳米颗粒大小有关,范围从 515-520 nm(5 nm 颗粒)至 572 nm(100 nm 颗粒)。

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

闪点(F)

Not applicable

闪点(C)

Not applicable

分析证书

原产地证书 (CofO)

Motao Zhu et al.
ACS nano, 14(3), 3703-3717 (2020-02-15)
Engineered nanoparticles could trigger inflammatory responses and potentiate a desired innate immune response for efficient immunotherapy. Here we report size-dependent activation of innate immune signaling pathways by gold (Au) nanoparticles. The ultrasmall-size (<10 nm) Au nanoparticles preferentially activate the NLRP3...
Gold nanoparticles surface-functionalized with paclitaxel drug and biotin receptor as theranostic agents for cancer therapy
Heo DN, et al.
Biomaterials, 33(3), 856-866 (2012)
Colorimetric biosensing of pathogenss using gold nanoparticles
Verma MS, et al.
Biotechnology Advances, 33(6), 666-680 (2015)
Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis
Li Z, et al.
Journal of Medical Virology, 33(6), 666-680 (2020)
Optimizing use of theranostic nanoparticles as a life-saving strategy for treating COVID-19 patients
Itani R, et al.
Theranostics, 10(13), 5932-5932 (2020)

技术文章

2D Materials Matter: A Perspective on Biosensing Applications

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