Merck
All Photos(2)

900555

Sigma-Aldrich

N -异氰亚氨基)三苯磷

95%

Synonym(s):
Pinc
Empirical Formula (Hill Notation):
C19H15N2P
CAS Number:
Molecular Weight:
302.31
MDL编号:

质量水平

100

测定

95%

形式

solid

application(s)

peptide synthesis

InChI

1S/C19H15N2P/c1-20-21-22(17-11-5-2-6-12-17,18-13-7-3-8-14-18)19-15-9-4-10-16-19/h2-16H

InChI key

NIDTXBFHPXMXTR-UHFFFAOYSA-N

应用

尽管对其治疗和其他生物学应用越来越感兴趣,环状拟肽的合成仍具有挑战性。正如Andrei Yudin实验室所报道的那样,(N-异氰亚氨基)三苯基磷(Pinc
)能在两性离子控制下从线性肽和醛生成肽大环。所得的肽含有1,3,4-恶二唑,其膜渗透性、亲脂性和水溶性均提高。
通过改变醛基可以引入不同的官能团,最初的工作使用了丙醛 ( 538124 )、苯乙醛 ( 107395 ) 和异戊醛 ( 146455 )。

包装

5 g in glass bottle
500 mg in glass insert

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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