Merck
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901941

Sigma-Aldrich

Thiol poly(ethylene glycol)-block-poly(lactide-co-glycolide)

PEG average Mn 5,000, PLGA average Mn 15,000, lactide:glycolide 50:50

Synonym(s):
Thiol-PEG-b-PLGA, Thiol-PEG-PLGA
Linear Formula:
C3H7SO(C2H4O)nC2H4O[(C2H2O2)x(C3H4O2)y]m

描述

Identity: Conforms to structure

形式

powder

投料比

lactide:glycolide 50:50
lactide:glycolide 50:50±5 (by NMR)

分子量

PEG Mn 4000-6000  g/mol (by NMR)
PEG average Mn 5,000
PLGA Mn 13500-16500 g/mol (by NMR)
PLGA average Mn 15,000

颜色

white

储存温度

−20°C

Related Categories

应用

Thiol poly(ethylene glycol)-block-poly(lactide-co-glycolide) is a thiol-functionalized, biocompatible, amphiphilic block copolymer. Due to its self-assembling properties, this material can be used in the formation of nanoparticles for drug delivery. Additionally, due to the thiol-functionalization of the PEG block, this material can be used to rapidly covalently conjugate biomolecules, API, or targeting ligands. Potential uses include the targeted and/or controlled release of cancer drugs, anti-inflammatory drugs, antibiotics, or anaesthetic agents.

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

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