Merck
All Photos(1)

927554

Sigma-Aldrich

MI-alkyne

≥95%

All Photos(1)
Synonym(s):
N-(2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)hex-5-ynamide
Empirical Formula (Hill Notation):
C12H14N2O3
Molecular Weight:
234.25

质量水平

100

检测方案

≥95%

储存温度

−20°C

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MI-alkyne ≥95%

Sigma-Aldrich

927554

MI-alkyne

HMP-alkyne ≥95%

Sigma-Aldrich

930466

HMP-alkyne

AlkFAA-alkyne ≥95%

Sigma-Aldrich

927538

AlkFAA-alkyne

ArVS-alkyne ≥95%

Sigma-Aldrich

927589

ArVS-alkyne

assay

≥95%

assay

≥95%

assay

≥95%

assay

≥95%

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

应用

MI-alkyne is a Michael acceptor probe that can be used to lable cysteines. A method was developed using cysteine-reactive compounds including this one to allow for unbiased analysis of proteomic data in quantitave applications (Zanon et al. 2021). The method uses light or heavy labeling with the isotopically labelled desthiobiotin azide (isoDTB) tag for mass spectrometry analysis (Zanon et al. 2020). Analysis then uses the isotopic tandem orthogonal proteolysis activity-based protein profiling (isoTOP-ABPP) workflow (Weerapana et al. 2010, Backus et al. 2016).

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

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