所有图片(1)

D126608

Sigma-Aldrich

2,6-二异丙基苯酚

97%

别名:
普鲁泊福, 2,6-双(1-甲基乙基)苯酚, 2,6-二异丙基苯酚
线性分子式:
[(CH3)2CH]2C6H3OH
CAS号:
分子量:
178.27
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

蒸汽压

5.6 mmHg ( 100 °C)

质量水平

100

测定

97%

折射率

n20/D 1.514 (lit.)

bp

256 °C/764 mmHg (lit.)

mp

18 °C (lit.)

密度

0.962 g/mL at 25 °C (lit.)

SMILES string

CC(C)c1cccc(C(C)C)c1O

InChI

1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3

InChI key

OLBCVFGFOZPWHH-UHFFFAOYSA-N

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一般描述

2,6-二异丙基苯酚(一种强疏水取代苯酚)是一种新型静脉麻醉剂。已研究 2,6-二异丙基苯酚(异丙酚)的抗氧化属性。2,6-二异丙基苯酚是一种有效的静脉注射催眠药,广泛用于麻醉诱导和维持以及重症监护病房的镇静。用于全身麻醉的诱导和维持。

应用

2,6-二异丙基苯酚是研究其对离体大鼠肝线粒体氧化磷酸化作用的合适试剂。是制备双(2,6-二异丙基苯氧基)双(2-甲基-8-喹啉)钛 (IV) 配合物的合适试剂。

包装

5, 100 g in glass bottle

象形图

Exclamation mark

警示用语:

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK Germany

WGK 3

闪点(F)

235.4 °F - closed cup

闪点(C)

113 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

分析证书

原产地证书 (CofO)

C Frenkel et al.
European journal of pharmacology, 208(1), 75-79 (1991-09-12)
Single sodium channels from human brain cortex tissue were incorporated into voltage-clamped planar lipid bilayers in the presence of batrachotoxin and studied with various doses of the new anaesthetic compound propofol (2,6-diisopropylphenol). Propofol was found to depress two major sodium...
Configurational rearrangements in cis-M (AA)2X2, cis-M (AA)2XY, and cis-M(AB)2X2 complexes.
Bickley DG and Serpone N.
Inorganic Chemistry, 18(8), 2200-2204 (1979)
M Rigoulet et al.
European journal of biochemistry, 241(1), 280-285 (1996-10-01)
We investigated the effects of 2,6-diisopropylphenol on oxidative phosphorylation of isolated rat liver mitochondria. Diisopropylphenol strongly inhibits state-3 and uncoupled respiratory rates, when glutamate and malate are the substrates, as a direct consequence of the limitation of electron transfer at...
P G Murphy et al.
British journal of anaesthesia, 68(6), 613-618 (1992-06-01)
We have examined in vitro the antioxidant properties of 2,6-diisopropylphenol. In studies using electron spin resonance spectroscopy we have demonstrated that 2,6-diisopropylphenol acts as an antioxidant by reacting with free radicals to form a phenoxyl radical--a property common to all...
Paul E Marik
Current pharmaceutical design, 10(29), 3639-3649 (2004-12-08)
Propofol (2, 6-diisopropylphenol) is a potent intravenous hypnotic agent which is widely used for the induction and maintenance of anesthesia and for sedation in the intensive care unit. Propofol is an oil at room temperature and insoluble in aqueous solution....

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