Radiolabeling of monoclonal antibodies and fragments with technetium and rhenium.
G L Griffiths et al.
Bioconjugate chemistry, 3(2), 91-99 (1992-03-01)
Mini reviews in medicinal chemistry, 4(1), 61-68 (2004-02-03)
The favourable nuclear properties of copper-67 and rhenium-188 for therapeutic application are described, together with methods for the chemical synthesis of a number of derivatives. Survival from invasive bladder cancer has changed little over the past 20 years. The intravesicular...
R Klett et al.
Rheumatology (Oxford, England), 46(10), 1531-1537 (2007-06-29)
Hypertrophy and inflammation of the synovium with various underlying pathologies - such as rheumatoid arthritis, osteoarthritis, haemophilia and spondyloarthropathy - can be treated successfully by radiosynoviorthesis (RSO). For medium-sized joints (shoulder, elbow, wrist, hip and ankle), the radionuclide of choice...
Peter Wolohan et al.
Steroids, 72(3), 247-260 (2007-02-07)
OPLS all atom force field parameters were developed in order to model a diverse set of novel rhenium based estrogen receptor ligands whose relative binding affinities (RBA) to the estrogen receptor alpha isoform (ERalpha) with respect to 17beta-estradiol were available....
Chimia, 64(4), 259-265 (2010-12-09)
Transition metal complexes of rhenium and technetium find wide application in nuclear medicine and the chemistry of these elements is still the focus of intense research efforts. For therapeutic and diagnostic applications, currently much attention is dedicated to the development...