Merck

M70800

Sigma-Aldrich

3-甲基-1-苯基-2-吡唑啉-5-酮

99%

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别名:
依达拉奉, 5-甲基-2-苯基-2,4-二氢-3-H-吡唑-3-酮
Empirical Formula (Hill Notation):
C10H10N2O
CAS号:
分子量:
174.20
Beilstein:
609575
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

99%

形式

powder, crystals or chunks

bp

287 °C/265 mmHg (lit.)

mp

126-128 °C (lit.)

application(s)

peptide synthesis

SMILES string

CC1=NN(C(=O)C1)c2ccccc2

InChI

1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3

InChI key

QELUYTUMUWHWMC-UHFFFAOYSA-N

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此商品
Y00011381040016443300
Phenazone impurity A European Pharmacopoeia (EP) Reference Standard

Y0001138

安替比林杂质A

Antipyrine Related Compound A United States Pharmacopeia (USP) Reference Standard

USP

1040016

3-甲基-1-苯基-2-吡唑啉-5-酮

MCI-186 A free radical scavenger and antioxidant that reduces post-ischemic brain injury.

Sigma-Aldrich

443300

MCI-186

form

powder, crystals or chunks

form

-

form

-

form

solid

mp

126-128 °C (lit.)

mp

126-128 °C (lit.)

mp

126-128 °C (lit.)

mp

-

bp

287 °C/265 mmHg (lit.)

bp

287 °C/265 mmHg (lit.)

bp

287 °C/265 mmHg (lit.)

bp

-

application(s)

peptide synthesis

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

应用

3-甲基-1-苯基-2-吡唑啉-5-酮可用于:
  • ESI/MALDI-MS检测还原性碳水化合物的试剂
  • 提高还原性单糖和寡糖的敏感性,便于随后用毛细管区带电泳进行测定
  • 在用高效液相色谱(HPLC)分析之前,对 丹参、盐酸川芎嗪和葡萄糖注射液中单糖组分进行柱前衍生化。

ESI/MALDI -MS检测还原性碳水化合物的试剂。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 1

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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Fa-Huan Ge et al.
Journal of analytical methods in chemistry, 2017, 9245620-9245620 (2017-05-11)
Salvia miltiorrhiza, liguspyragine hydrochloride, and glucose injection (SLGI) was made of Salvia miltiorrhiza Bge., liguspyragine hydrochloride, glucose, and glycerin. There were many kinds of monosaccharide components in SLGI, which might be from the raw material and Salvia miltiorrhiza Bge. Separation
Influence of the labeling group on ionization and fragmentation of carbohydrates in mass spectrometry
Lattova E, et al.
Journal of the American Society For Mass Spectrometry, 16(5), 683-696 (2005)
Capillary zone electrophoresis of reducing mono-and oligo-saccharides as the borate complexes of their 3-methyl-1-phenyl-2-pyrazolin-5-one derivatives
Honda S, et al.
Carbohydrate Research, 215(1), 193-198 (1991)
Xin-Gang Du et al.
Journal of natural products, 73(8), 1422-1426 (2010-08-04)
Two new dimeric xanthone O-glycosides, puniceasides A (1) and B (2), a new trimeric O-glycoside, puniceaside C (3), and two new trimeric C-glycosides, puniceasides D (4) and E (5), together with 12 known xanthones were isolated from the entire plant
Hidehiko Nakagawa et al.
Bioorganic & medicinal chemistry letters, 16(23), 5939-5942 (2006-09-26)
We synthesized various 3-methyl-1-phenyl-5-pyrazolone (edaravone) derivatives and evaluated their oxidation potential and hydroxyl radical scavenging activity. It was found 3-methyl-1-(pyridin-2-yl)-5-pyrazolone had a much higher ability to scavenge the radical than did edaravone itself. Its efficient radical scavenging activity was assumed

商品

蛋白质的结构修饰对于活细胞是必不可少的。发生调节异常时,它们往往是会引发疾病。聚糖是生物系统中许多结构变异的原因,它们在细胞表面的表现通常被称为“糖”。

Structural modifications of proteins are essential to living cells. When aberrantly regulated they are often the basis of disease. Glycans are responsible for much of the structural variation in biologic systems, and their representation on cell surfaces is commonly called the “glycome.”

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