Merck
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QBD10008

Sigma-Aldrich

Biotin-dPEG®12-TFP ester

Empirical Formula (Hill Notation):
C43H69F4N3O16S
Molecular Weight:
992.08
PubChem化学物质编号:
NACRES:
NA.22

测定

>90%

形式

solid or viscous liquid

reaction suitability

reaction type: Biotinylations
reaction type: Biotinylations
reactivity: amine reactive

reagent type: cross-linking reagent

聚合物结构设计

shape: linear
functionality: monofunctional

运输

ambient

储存温度

−20°C

SMILES string

O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC1C2NC(NC2CS1)=O)=O)OC3=C(C(F)=CC(F)=C3F)F

特点和优势

Biotin-dPEG®12-TFP ester has 2,3,5,6-tetrafluorophenyl (TFP) moiety whcih hydrolyze more slowly than NHS esters in aqueous media and is more reactive towards amines than NHS esters. The single molecular weight Biotin-dPEG®12-TFP ester has a long spacer of precise length (47.6 Å) between the biotin moiety and the labeled molecule. This dPEG spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the PEG spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.

法律信息

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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