Merck
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QBD10200

Sigma-Aldrich

NHS-dPEG ® 4 -生物素

Empirical Formula (Hill Notation):
C25H40N4O10S
CAS Number:
Molecular Weight:
588.67
PubChem化学物质编号:
NACRES:
NA.22

测定

>90%

形式

solid or viscous liquid

reaction suitability

reaction type: Biotinylations
reactivity: amine reactive

reagent type: cross-linking reagent

聚合物结构设计

shape: linear
functionality: monofunctional

运输

ambient

储存温度

−20°C

SMILES string

O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCNC(CCCCC2C3NC(NC3CS2)=O)=O

一般描述

NHS-dPEG®4-biotin is a water-soluble cross-linking reagent used in biotinylation reactions. The N-hydroxysuccinimidyl (NHS) moiety of NHS-dPEG®4-biotin forms a stable amide bond with free primary amines, such as the amines on the side chain of lysine. The biotin moiety is used in a variety of applications, including labeling, supramolecular building, affinity chromatography, pull-down assays, and the production of biotinylated antibodies.

特点和优势

NHS-dPEG ® 4 -生物素被广泛用于标记含有游离胺的分子。单分子量 NHS-dPEG ® 4 -生物素在生物素部分和标记的分子之间有一段长度精确 (19.2 Å) 的长间隔区。该 dPEG ® 垫片使生物素标记物具有高度水溶性。对于生物素化的多肽和蛋白,dPEG ® 间隔物显著减少了修饰分子的聚集和沉淀,减少了分子的非特异性结合,这两者都是已经用广泛使用的 NHS-LC-biotin 生物素化的分子的常见问题。

法律信息

受美国 7,888,536 B2 号专利保护的产品
dPEG is a registered trademark of Quanta BioDesign

储存分类代码

11 - Combustible Solids

闪点(F)

Not applicable

闪点(C)

Not applicable

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Certificate of Origin

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