Merck
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文件

QBD10244

Sigma-Aldrich

Amino-dPEG®4-acid

>95% (HPLC)

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别名:
Amino-PEG-acid, Amino-PEG4-acid, CA(PEG)4, Carboxy-PEG4-amine, NH2-PEG4-COOH
Empirical Formula (Hill Notation):
C11H23NO6
分子量:
265.30
MDL编号:
MFCD11041129

检测方案

>95% (HPLC)

形式

solid or viscous liquid

reaction suitability

reaction type: Pegylations

聚合物结构设计

shape: linear
functionality: heterobifunctional

运输

ambient

储存温度

−20°C

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此商品
QBD10760QBD11626QBD11581
Amino-dPEG®4-acid >95% (HPLC)

Sigma-Aldrich

QBD10244

Amino-dPEG®4-acid

t-Boc-N-amido-dPEG®8-acid >95% (HPLC)

Sigma-Aldrich

QBD10760

t-Boc-N-amido-dPEG®8-acid

MAL-dPEG®4-Glu(TFP ester)-NH-dPEG®4-Glu(TFP ester)-NH-m-dPEG®24 >90% (HPLC)

Sigma-Aldrich

QBD11626

MAL-dPEG®4-Glu(TFP ester)-NH-dPEG®4-Glu(TFP ester)-NH-m-dPEG®24

MAL-dPEG®4-Glu(TFP ester)-NH-m-dPEG®24 >90% (HPLC)

Sigma-Aldrich

QBD11581

MAL-dPEG®4-Glu(TFP ester)-NH-m-dPEG®24

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

reaction suitability

reaction type: Pegylations

reaction suitability

reaction type: Pegylations

reaction suitability

reaction type: Pegylations

reaction suitability

reaction type: Pegylations

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: Y-shape
functionality: heterobifunctional

polymer architecture

shape: Y-shape
functionality: heterobifunctional

shipped in

ambient

shipped in

ambient

shipped in

ambient

shipped in

ambient

特点和优势

Amino-dPEG4-acid has a primary amine and propionic acid terminating opposite ends of a 16-atoms long (18.0 Å) polyethylene glycol (PEG) spacer. The single molecular weight PEG spacer is discrete (Ð = 1). Moreover, it is highly hydrophilic, and it imparts hydrophilicity to conjugates that incorporate it. Amino-dPEG4-acid is useful in many different applications, including peptide synthesis, surface modification, dendrimer construction, and small molecule modification.

法律信息

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

Certificates of Analysis (COA)

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Kohei Sano et al.
Bioconjugate chemistry, 24(5), 811-816 (2013-04-23)
The ability to switch optical imaging probes from the quenched (off) to the active state (on) has greatly improved target to background ratios. The optimal activation efficiency of an optical probe depends on complete quenching before activation and complete dequenching
Lijun Wang et al.
Molecular pharmaceutics, 6(1), 231-245 (2008-12-11)
This report describes the synthesis of two cyclic RGD (Arg-Gly-Asp) conjugates, HYNIC-2PEG(4)-dimer (HYNIC = 6-hydrazinonicotinyl; 2PEG(4)-dimer = E[PEG(4)-c(RGDfK)](2); and PEG(4) = 15-amino-4,7,10,13-tetraoxapentadecanoic acid) and HYNIC-3PEG(4)-dimer (3PEG(4)-dimer = PEG(4)-E[PEG(4)-c(RGDfK)](2)), and evaluation of their (99m)Tc complexes [(99m)Tc(HYNIC-2PEG(4)-dimer)(tricine)(TPPTS)] ((99m)Tc-2PEG(4)-dimer: TPPTS = trisodium triphenylphosphine-3,3',3''-trisulfonate)
Mark Lefever et al.
Bioconjugate chemistry, 21(10), 1773-1778 (2010-09-04)
A novel method of linking haptens to deoxycytidine 5'-triphosphate via microwave-mediated bisulfate-catalyzed transamination with hydrazine has been developed. This method enables the tethering of small molecule haptens to dCTP via a discrete polyethylene glycol (PEG) spacer, yielding N(4)-aminodeoxycytidine 5'-triphosphate-dPEG-haptens. This
Jiyun Shi et al.
Bioconjugate chemistry, 20(4), 750-759 (2009-03-27)
Radiolabeled cyclic RGD (Arg-Gly-Asp) peptides represent a new class of radiotracers with potential for early tumor detection and noninvasive monitoring of tumor metastasis and therapeutic response in cancer patients. This article describes the synthesis of two cyclic RGD peptide dimer

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