Merck

QBD10314

Sigma-Aldrich

MAL-dPEG®24-NHS 酯

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Empirical Formula (Hill Notation):
C62H111N3O31
分子量:
1394.55
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

检测方案

>90%

形式

solid or viscous liquid

reaction suitability

reactivity: thiol reactive
reagent type: cross-linking reagent
reactivity: amine reactive

聚合物结构设计

shape: linear
functionality: heterobifunctional

运输

ambient

储存温度

−20°C

SMILES string

O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)CCN2C(C=CC2=O)=O

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此商品
QBD11303QBD10554QBD10379
MAL-dPEG®24-NHS ester

Sigma-Aldrich

QBD10314

MAL-dPEG®24-NHS 酯

MAL-dPEG®24-TFP ester

Sigma-Aldrich

QBD10554

MAL-dPEG®24-TFP ester

SPDP-dPEG®24-NHS ester

Sigma-Aldrich

QBD10379

SPDP-dPEG®24-NHS ester

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

reaction suitability

reactivity: thiol reactive, reagent type: cross-linking reagent
reactivity: amine reactive

reaction suitability

reactivity: thiol reactive, reagent type: cross-linking reagent
reactivity: amine reactive

reaction suitability

reactivity: thiol reactive, reagent type: cross-linking reagent
reactivity: amine reactive

reaction suitability

reactivity: thiol reactive, reagent type: cross-linking reagent
reactivity: amine reactive

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

shipped in

ambient

shipped in

ambient

shipped in

ambient

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

特点和优势

MAL-dPEG® 24-NHS酯是一种杂双功能线性交联剂,在单分子量dPEG®间隔臂的一端包含一个马来酰亚胺基团,另一端包含胺反应性活性酯。dPEG之后的数字® 指间隔臂中存在的间隔单元的确切数量。马来酰亚胺基可容易且特异地与pH 6.5-7.5的水性介质中的游离巯基发生反应。N-羟基琥珀酰亚胺(NHS)酯被广泛用于与伯胺的反应。NHS-胺反应可以在水性或有机溶剂中进行。dPEG® 间隔臂是亲水的且不具有免疫原性。由于它是单一分子量的产品,因此可以为用户提供精确的空间控制。dPEG® 间隔臂还可改善水溶性、降低免疫原性、并增加缀合物的流体动力学体积。增加的流体动力学体积能导致更长的体内血清半衰期。

法律信息

受美国专利#7,888,536 B2保护的产品
dPEG is a registered trademark of Quanta BioDesign

储存分类代码

11 - Combustible Solids

闪点(F)

Not applicable

闪点(C)

Not applicable


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