Merck
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QBD10501

Sigma-Aldrich

Azido-dPEG®4-NHS ester

Empirical Formula (Hill Notation):
C15H24N4O8
CAS Number:
Molecular Weight:
388.37
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

测定

>90%

形式

solid or viscous liquid

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent
reaction type: click chemistry

聚合物结构设计

shape: linear
functionality: heterobifunctional

运输

ambient

储存温度

−20°C

SMILES string

O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCN=[N+]=[N-]

特点和优势

The azido-dPEG®4-NHS ester contains an azide function on one end of a single molecular weight dPEG® spacer (17.7 Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. NHS ester readily reacts with amines in aqueous solution or organic solvent. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

法律信息

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

储存分类代码

13 - Non Combustible Solids

闪点(F)

Not applicable

闪点(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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