Merck

QBD10505

Sigma-Aldrich

叠氮基-dPEG®12-NHS酯

Empirical Formula (Hill Notation):
C31H56N4O16
分子量:
740.79
MDL编号:
PubChem化学物质编号:

检测方案

>90%

形式

solid or viscous liquid

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent
reaction type: click chemistry

聚合物结构设计

shape: linear
functionality: heterobifunctional

运输

ambient

储存温度

−20°C

SMILES string

O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])ON1C(CCC1=O)=O

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此商品
QBD10569QBD10571QBD10573
form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

reaction suitability

reaction type: click chemistry, reagent type: cross-linking reagent
reaction type: click chemistry

reaction suitability

reaction type: click chemistry, reagent type: cross-linking reagent
reaction type: click chemistry

reaction suitability

reaction type: click chemistry, reagent type: cross-linking reagent
reaction type: click chemistry

reaction suitability

reaction type: click chemistry, reagent type: cross-linking reagent
reaction type: click chemistry

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

shipped in

ambient

shipped in

ambient

shipped in

ambient

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

特点和优势

叠氮基-dPEG®8-NHS酯在单个分子量dPEG®间隔基(47.2Å)的一端包含叠氮化物官能团,在间隔基的另一端包含NHS酯基。dPEG®间隔基具有亲水性和非免疫原性,提高了靶标分子的水溶性,同时降低免疫原性和增加靶标的流体动力学体积。N-羟基琥珀酰亚胺(NHS)酯在水溶液或有机溶剂中容易与胺类反应。叠氮化物基团在众所周知的点击化学反应中与炔烃反应。点击化学反应通过铜(I)或钌催化或与某些类型的炔烃伙伴的应变催化反应进行。

法律信息

受美国专利#7,888,536 B2保护的产品
dPEG is a registered trademark of Quanta BioDesign

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable


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