Merck
  • QBD10867
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QBD10867

Sigma-Aldrich

SPDP-dPEG®36-NHS ester

>95% (HPLC)

Synonym(s):
OPSS-PEG1500-NHS ester, OPSS-PEG36-NHS ester, SPDP-PEG-NHS ester, SPDP-PEG36-NHS ester
Empirical Formula (Hill Notation):
C87H161N3O41S2
Molecular Weight:
1969.33
MDL编号:

检测方案

>95% (HPLC)

形式

solid or viscous liquid

reaction suitability

reaction type: Pegylations

聚合物结构设计

shape: linear
functionality: heterobifunctional

运输

ambient

储存温度

−20°C

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QBD10910QBD10866QBD10140
SPDP-dPEG®36-acid >95% (HPLC)

Sigma-Aldrich

QBD10866

SPDP-dPEG®36-acid

assay

>95% (HPLC)

assay

>95% (HPLC)

assay

>95% (HPLC)

assay

>95% (HPLC)

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

form

solid or viscous liquid

reaction suitability

reaction type: Pegylations

reaction suitability

reaction type: Pegylations

reaction suitability

reaction type: Pegylations

reaction suitability

reaction type: Pegylations

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: monofunctional

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

shipped in

ambient

shipped in

ambient

shipped in

ambient

特点和优势

SPDP-dPEG36-NHS ester is an amphiphilic, water-soluble PEGylation reagent that is designed to crosslink amines and free thiols. SPDP (also referred to as orthopyridyl disulfide, or OPSS) reacts with sulfhydryl groups to form disulfide bonds. The N-hydroxysuccinimidyl (NHS) ester reacts with free amines to form amide bonds. The single molecular weight, discrete chain length polyethylene glycol (dPEG) chain is 115 atoms (137.8 Å) long. SPDP-dPEG36-NHS ester is used like SPDP and its related hydrophobic products. However, the water-soluble dPEG product prevents hydrophobicity-triggered precipitation of compounds to which it is conjugated. SPDP-dPEG36-NHS ester is a monodisperse equivalent of the polymeric PEG1500.

法律信息

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable


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