Merck

QBD11487

Sigma-Aldrich

MAL-dPEG®24-Tris(-dPEG®24-Tris(m-dPEG®24)3)3

>95% (HPLC)

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别名:
9-arm mPEG 14K PEG1000-MAL, Branched Maleimide-PEG-m, Branched mPEG-maleimide, MAL-PEG24-Tris(-PEG24-Tris(m-PEG24)3)3
Empirical Formula (Hill Notation):
C704H1386N18O343
分子量:
15592.45

检测方案

>95% (HPLC)

形式

solid or viscous liquid

reaction suitability

reaction type: Pegylations

聚合物结构设计

functionality: monofunctional

运输

ambient

储存温度

−20°C

特点和优势

MAL-dPEG24-Tris (-dPEG24-Tris (m-dPEG24)3)3 is a sulfhydryl-reactive, multibranched, monodispersed PEG product. The product is built around tris. One arm terminates in a maleimide group that reacts selectively with free thiols in a click chemistry type of reaction. Nine branches terminate in methyl groups. The molecular weight of the product is 15,592 Daltons. The amphiphilic PEG imparts tremendous water solubility to conjugate molecules and expands their hydrodynamic volume sufficiently to eliminate the renal clearance of the conjugates. The end-to-end length of the dPEG spacer from the maleimido olefin to the terminal methyl group on each branch is 245 atoms, with an average distance of 171.2 Å.

法律信息

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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