Inducible release of particulates from liposomes using the mechanosensitive channel of large conductance and l-alpha-lysophosphatidylcholine
Foo A, et al.
European Biophysics Journal, 44(7), 521-530 (2015)
Said Izreig et al.
Cell reports. Medicine, 1(2), 100014-100014 (2020-06-02)
Cancer cells display metabolic plasticity to survive stresses in the tumor microenvironment. Cellular adaptation to energetic stress is coordinated in part by signaling through the liver kinase B1 (LKB1)-AMP-activated protein kinase (AMPK) pathway. Here, we demonstrate that miRNA-mediated silencing of...
Selective extraction of phosphatidylcholine from lecithin by supercritical carbon dioxide/ethanol mixture
Teberikler L, et al.
Journal of the American Oil Chemists' Society, 78(2), 115-120 (2001)
Michael A Goren et al.
Biochemistry, 50(41), 8853-8861 (2011-09-09)
The substrate selectivity of four Trypanosoma brucei sphingolipid synthases was examined. TbSLS1, an inositol phosphorylceramide (IPC) synthase, and TbSLS4, a bifunctional sphingomyelin (SM)/ethanolamine phosphorylceramide (EPC) synthase, were inactivated by Ala substitutions of a conserved triad of residues His210, His253, and...
Dalian Zhong et al.
Biochemistry, 52(32), 5415-5420 (2013-07-24)
The bacterial mechanosensitive channel of large conductance (MscL) directly senses and responds to membrane tension. It serves as an "emergency release valve" upon acute decreases in the osmotic environment, thus preventing cell lysis. It is one of the best studied...