700010P

Avanti

15α-hydroxycholestene

5α-cholest-8(14)-ene-3β,15α-diol, powder

别名:
3b,15a-diol-5a-cholest-8(14)-ene
Empirical Formula (Hill Notation):
C27H46O2
CAS号:
分子量:
402.65
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (700010P-5mg)

mfr. no.

Avanti Polar Lipids, 700010P

shipped in

dry ice

storage temp.

−20°C

General description

15α-hydroxycholestene is the oxidized derivative of cholesterol.

Biochem/physiol Actions

15α-hydroxycholestene levels are modulated in the relapsing-remitting multiple sclerosis (RRMS) and secondary progressive multiple sclerosis (SPMS). It is implicated in autoimmune encephalomyelitis (EAE).

Packaging

5 mL Amber Glass Screw Cap Vial (700010P-5mg)

RIDADR

NONH for all modes of transport

Toll-like receptor 2 and poly (ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE
Farez MF, et al.
Nature Immunology, 10(9), 958-958 (2009)
Are 15-oxygenated sterols present in the human circulation?
Griffiths WJ and Wang Y
Journal of Lipid Research, 52(1), 4-5 (2011)
Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis
Quintana FJ, et al.
Proceedings of the National Academy of Sciences of the USA, 105(48), 18889-18894 (2008)

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