700096P

Avanti

7α,24(S)-dihydroxycholesterol

7α,24(S)-dihydroxycholesterol, powder

别名:
cholest-5-ene-3β,7α,24(S)-triol
Empirical Formula (Hill Notation):
C27H46O3
CAS号:
分子量:
418.65
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (700096P-1mg)

mfr. no.

Avanti Polar Lipids, 700096P

shipped in

dry ice

storage temp.

−20°C

General description

7α,24(S)-dihydroxycholesterol (24(S)-dihydroxycholesterol) is synthetically synthesized via from E-α, β-enone from the starting compounds Arsonium ylide and J-tert-butyldimethylsilyloxy-bisnor-5-cholenaldehyde. This undergoes further changes to form 7α,24(S)-dihydroxycholesterol.

Biochem/physiol Actions

7α,24(S)-dihydroxycholesterol (24(S)-dihydroxycholesterol) is a ligand for liver X receptor (LXR) and binds to the ligand binding domain of LXRα and LXRβ.

Packaging

5 mL Amber Glass Screw Cap Vial (700096P-1mg)

RIDADR

NONH for all modes of transport

分析证书
原产地证书 (CofO)
Simple, stereocontrolled syntheses of 24 (S), 25-epoxy-22 (R)-hydroxycholesterol, 22 (R), 24 (S)-dihydroxycholesterol and diastereomers, new ligands for binding and activation of LXRs
Corey EJ and Grogan MJ
Tetrahedron Letters, 39(51), 9355-9356 (1998)

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