700131P

Avanti

24S,27-dihydroxycholesterol

(25S)-cholest-5-en-3β,24S,27-triol, powder

Empirical Formula (Hill Notation):
C27H46O3
CAS号:
分子量:
418.65
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (700131P-1mg)

mfr. no.

Avanti Polar Lipids, 700131P

shipped in

dry ice

storage temp.

−20°C

General description

24S,27-dihydroxycholesterol differs from 24S-hydroxycholesterol in steroid nucleus by having an additional hydroxyl group. 24S,27-dihydroxycholesterol is derived from 24S-hydroxycholesterol in the presence of enzyme cholesterol 24-hydroxylase (P450 46A1).

Packaging

5 mL Amber Glass Screw Cap Vial (700131P-1mg)

RIDADR

NONH for all modes of transport

分析证书
原产地证书 (CofO)
Natalia Mast et al.
Biochemistry, 42(48), 14284-14292 (2003-12-03)
The known activity of cytochrome P450 46A1 (P450 46A1) is 24(S)-hydroxylation of cholesterol. This reaction produces biologically active oxysterol, 24(S)-hydroxycholesterol, and is also the first step in enzymatic degradation of cholesterol in the brain. We report here that P450 46A1...

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