791225P

Avanti

14:0 PE-DTPA(Cu)

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (copper salt), powder

Empirical Formula (Hill Notation):
C47H94CuN7O17P
CAS号:
分子量:
1123.81
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (791225P-5mg)

mfr. no.

Avanti Polar Lipids, 791225P

shipped in

dry ice

storage temp.

−20°C

General description

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid or 14:0 PE-DTPA is a synthetic phosphatidylethanolamine derivative.
Inclusion of copper (Cu2+) ions in bicelles in the form of a lipid chelate resulted in a 10-fold T1 reduction and 2.7-fold increase in S/N of spectra for static experiments. This improvement would allow 2D experiments on membrane proteins in aligned lipid bilayers that typically take 3 days to be completed in <1.5 days. The technique is particularly beneficial to the study of membrane disrupting/permeating systems (such as antimicrobial peptides, toxins, amyloid peptides, and fusion peptides) whose concentration cannot be increased, as they result in nonlamellar conditions.

Application

14:0 PE-DTPA(Cu) may be usedis suitable for use for liposome preparations and liposome labelling.

Packaging

5 mL Amber Glass Screw Cap Vial (791225P-5mg)

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

分析证书
原产地证书 (CofO)
Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer
Kang JY, et al.
Immunity, 31(6), 873-884 (2009)
Kazutoshi Yamamoto et al.
Journal of the American Chemical Society, 132(20), 6929-6931 (2010-05-04)
Recent studies have demonstrated the abilities of solid-state NMR techniques to solve atomic-level-resolution structures and dynamics of membrane-associated proteins and peptides. However, high-throughput applications of solid-state NMR spectroscopy are hampered by long acquisition times due to the low sensitivity of...
Tumor targeting and imaging with dual-peptide conjugated multifunctional liposomal nanoparticles
Rangger C, et al.
International journal of nanomedicine, 8(6), 4659-4659 (2013)
Direct observation of the three regions in $\alpha$-synuclein that determine its membrane-bound behaviour
Fusco Giuliana, et al.
Nature Communications, 5, 3827-3827 (2014)
Rupa R Sawant et al.
Pharmaceutical research, 29(2), 375-383 (2011-08-17)
To evaluate and compare anticancer therapeutic effect of palmitoyl ascorbate liposomes (PAL) and free ascorbic acid (AA). Liposomes incorporating palmitoyl ascorbate (PA) were prepared and evaluated for PA content by HPLC. To elucidate mechanism of action of cell death in...

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