791639C

Avanti

15:0-18:1-d7-PS

1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phospho-L-serine (sodium salt), chloroform

Empirical Formula (Hill Notation):
C39H66 D7 NNaO10 P
分子量:
777.00
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

packaging

pkg of 1 × 1 mL (791639C-1mg)

mfr. no.

Avanti Polar Lipids, 791639C

concentration

1 mg/mL (791639C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH® LIPIDOMIX® Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.
1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phospho-L-serine (sodium salt) is a is a deuterated phospholipid. The lipid comprises phosphatidylserine attached to pentadecanoic acid and oleic acid. Oleic acid harbors the deuterium ions. Phosphatidylserine is a component of inner cell membrane and is present in metabolically active sites. It is enriched in myelin sheath and is an acidic phospholipid.

Application

15:0-18:1-d7-PS (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phospho-L-serine (sodium salt)) has been used:
  • as a component of extraction solvent for lipid isolation from biological samples
  • as an internal standard to spike cell lysate and to quantify lipid species using fourier transform mass spectrometry (FTMS) analysis
  • as an internal standard to spike liver homogenate to quantify lipids by shotgun-electrospray ionization tandem mass spectrometry (ESI-MS)

Biochem/physiol Actions

Phosphatidylserine (PS) coordinates many regulatory functions and is a modulator of enzymes, channels and various receptors. PS supplementation provides relief from exercise induced stress. PS is essential for neurotransmission, prevents nerve cell deterioration and supports cognitive functionality.

Packaging

2 mL Amber Glass Sealed Ampule (791639C-1mg)

Legal Information

LIPIDOMIX is a registered trademark of Avanti Polar Lipids, Inc.
SPLASH is a registered trademark of Avanti Polar Lipids, Inc.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Target Organs

Central nervous system

RIDADR

UN 1888 6.1 / PGIII

WGK Germany

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

分析证书
原产地证书 (CofO)
Impact of plant polyphenols on triacylglycerols and phos-pholipids in rat liver fed with high fat diet
Ma HF, et al.
OIL CROP SCIENCE, 4, 251-264 (2017)
Michael A Starks et al.
Journal of the International Society of Sports Nutrition, 5, 11-11 (2008-07-30)
Previous research has indicated that phosphatidylserine (PS) supplementation has the potential to attenuate the serum cortisol response to acute exercise stress. Equivocal findings suggest that this effect might be dose dependent. This study aimed to examine the influence of short-term...
Tong Liu et al.
Expert review of proteomics, 17(3), 233-242 (2020-04-21)
Background: Colorectal cancer (CRC) represents a third leading cause of cancer-related death worldwide. The reliable diagnostic biomarkers for detecting CRC at early stage is critical for decreasing the mortality.Method: A conjunctive lipidomic approach was employed to investigate the differences in...
Chuchu Wang et al.
Nature communications, 11(1), 1531-1531 (2020-03-27)
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using...
Michael J Glade et al.
Nutrition (Burbank, Los Angeles County, Calif.), 31(6), 781-786 (2015-05-03)
The aim of this study was to assess the roles and importance of phosphatidylserine (PS), an endogenous phospholipid and dietary nutrient, in human brain biochemistry, physiology, and function. A scientific literature search was conducted on MEDLINE for relevant articles regarding...

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