810152C

Avanti

14:0-12:0 NBD PE

1-myristoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoethanolamine, chloroform

Empirical Formula (Hill Notation):
C37H64N5O11P
CAS号:
分子量:
785.90
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

packaging

pkg of 1 × 1 mL (810152C-1mg)

mfr. no.

Avanti Polar Lipids, 810152C

concentration

1 mg/mL (810152C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

Nitrobenzoxadiazole phosphoethanolamine (NBD PE) is a fluorescent probe with NBD covalently attached to the headgroup of phosphatidylethanolamine. It localized at the membrane interface and mostly present in brain. Phosphoethanolamine is the second most abundant, metabolically related aminophospholipid.

Biochem/physiol Actions

Phosphoethanolamine of cardiac myocytes is useful in the prevention of cell damage after ischemia. Nitrobenzoxadiazole phosphoethanolamine (NBD PE) is used to monitor the Red edge excitation shift (REES) effects due to its unique motional and dielectric properties.

Packaging

5 mL Amber Glass Screw Cap Vial (810152C-1mg)

RIDADR

UN 1888 6.1 / PGIII

分析证书
原产地证书 (CofO)
Application of NBD-labeled lipids in membrane and cell biology
Fluorescent methods to study biological membranes, 37-50 (2012)
S C Lopes et al.
Biochimica et biophysica acta. Biomembranes, 1861(6), 1152-1161 (2019-03-07)
Mitochondrial membranes are pointed out as the site of cardiotoxic action of local anaesthetics. Its three main phospholipids components are phosphatidylcholine, phosphatidylethanolamine and cardiolipin. Cardiolipins, in eukaryotes, are only found in mitochondria and are essential for the maintenance of its...
Jean E Vance et al.
Biochimica et biophysica acta, 1831(3), 543-554 (2012-09-11)
Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are metabolically related membrane aminophospholipids. In mammalian cells, PS is required for targeting and function of several intracellular signaling proteins. Moreover, PS is asymmetrically distributed in the plasma membrane. Although PS is highly enriched in...

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