810192C

Avanti

16:0-06:0 NBD PS

1-palmitoyl-2-{6-(7-nitro-2-1,3-benzoxadiazol-4-yl)aminohexanoyl}-sn-glycero-3-phosphoserine (ammonium salt), chloroform

Empirical Formula (Hill Notation):
C34H59N6O13P
CAS号:
分子量:
790.84
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

packaging

pkg of 1 × 1 mL (810192C-1mg)

mfr. no.

Avanti Polar Lipids, 810192C

concentration

1 mg/mL (810192C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylserine (PS) is a minor phospholipid present in the membranes of prokaryotic and eukaryotic cells. It comprises 2-10% of total phospholipids, enriched in brain. NBD PS is labelled at the headgroup of PS with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD).

Application

16:0-06:0 NBD PS or 1-palmitoyl-2-{6-(7-nitro-2-1,3-benzoxadiazol-4-yl)aminohexanoyl}-sn-glycero-3-phosphoserine (ammonium salt) is suitable to measure the enzyme specificity of lipoteichoic acid (LTA) synthase (LtaS) and in liposomes to determine the role of phospholipid scramblase 1 (PLSCR1) in phospholipid scrambling.

Biochem/physiol Actions

Phosphatidylserine (PS) contributes to the clearance of apoptotic cells. It is involved in maintaining the nerve cell membrane and myelin sheath. It is associated with cognitive disability in Alzheimer′s disease.

Packaging

5 mL Amber Glass Screw Cap Vial (810192C-1mg)

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Target Organs

Central nervous system

RIDADR

UN 1888 6.1 / PGIII

WGK Germany

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

分析证书
原产地证书 (CofO)
Nobuto Arashiki et al.
Biochemistry, 55(25), 3504-3513 (2016-06-09)
An asymmetric distribution of phospholipids in the membrane bilayer is inseparable from physiological functions, including shape preservation and survival of erythrocytes, and by implication other cells. Aminophospholipids, notably phosphatidylserine (PS), are confined to the inner leaflet of the erythrocyte membrane...
Maria Mercedes Palomino et al.
Microbiology (Reading, England), 159(Pt 11), 2416-2426 (2013-09-10)
The probiotic Gram-positive bacterium Lactobacillus casei BL23 is naturally confronted with salt-stress habitats. It has been previously reported that growth in high-salt medium, containing 0.8 M NaCl, leads to modifications in the cell envelope of this bacterium. In this study...
Jean E Vance et al.
Progress in lipid research, 44(4), 207-234 (2005-06-28)
Phosphatidylserine (PS) is a quantitatively minor membrane phospholipid that is synthesized by prokaryotic and eukaryotic cells. In this review we focus on genes and enzymes that are involved in PS biosynthesis in bacteria, yeast, plants and mammalian cells and discuss...
Mirka E Wörmann et al.
Molecular microbiology, 79(3), 566-583 (2011-01-25)
Lipoteichoic acid (LTA) is an important cell wall polymer in Gram-positive bacteria. The enzyme responsible for polyglycerolphosphate LTA synthesis is LtaS, first described in Staphylococcus aureus. Four LtaS orthologues, LtaS(BS) , YfnI, YqgS and YvgJ, are present in Bacillus subtilis....
Soumi Mukherjee et al.
Chemistry and physics of lipids, 127(1), 91-101 (2004-01-07)
Lipids that are labeled with the NBD (7-nitrobenz-2-oxa-1,3-diazol-4-yl) group are widely used as fluorescent analogues of native lipids in biological and model membranes to monitor a variety of processes. NBD-labeled lipids have previously been used to monitor the organization and...

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