810206P

Avanti

NBD Sphinganine

omega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R)-2-aminooctadecane-1,3-diol, powder

别名:
D-erythro-sphinganine-N-NBD; NBD-dihydrosphingosine
Empirical Formula (Hill Notation):
C24H41N5O5
CAS号:
分子量:
479.61
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 250 μg (810206P-250ug)
pkg of 1 × 50 μg (810206P-50UG)

mfr. no.

Avanti Polar Lipids, 810206P

shipped in

dry ice

storage temp.

−20°C

General description

Sphinganine, also called as dihydrosphingosine is a common sphingoid base in phospholipids.

Application

NBD Sphinganine or omega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R)-2-aminooctadecane-1,3-diol is suitable for the analysis of the dihydrosphingosine (DHS) localization to endoplasmic reticulum for the activation of activating transcription factor 6 (ATF6) protein.
NBD Sphinganine or omega (7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R)-2-aminooctadecane-1,3-diol is suitable for the analysis of the dihydrosphingosine (DHS) localization to endoplasmic reticulum for the activation of activating transcription factor 6 (ATF6) protein.

Packaging

5 mL PTFE Screw Cap Vial with Foil Bag Argon overpack (810206P-250ug)
5ML Glass Amber Screw Cap Vial (810206P-50UG)

RIDADR

NONH for all modes of transport

分析证书
原产地证书 (CofO)
Arvin B Tam et al.
Developmental cell, 46(3), 327-343 (2018-08-08)
The unfolded protein response (UPR) is induced by proteotoxic stress of the endoplasmic reticulum (ER). Here we report that ATF6, a major mammalian UPR sensor, is also activated by specific sphingolipids, dihydrosphingosine (DHS) and dihydroceramide (DHC). Single mutations in a previously...
Junliang Wan et al.
Journal of agricultural and food chemistry, 67(46), 12953-12961 (2019-10-23)
Most common sphingolipids are comprised of "typical" sphingoid bases (sphinganine, sphingosine, and structurally related compounds) and are produced via the condensation of l-serine with a fatty acyl-CoA by serine palmitoyltransferase. Some organisms, including mammals, also produce "atypical" sphingoid bases that...

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