C6-NBD ceramide is a fluorescent labelled compound, known to be useful for the detection of enzymatic action. C6-NBD ceramide is preferred over radioactive compounds.
C6-NBD Ceramide is suitable as a substrate for sphingomyelin synthase activity assay.
Ceramide is one of the products of sphingolipid metabolism. The members of ceramide synthases family are responsible for its synthesis. Each ceramide synthesized differs in its acyl chain length. Ceramides possess a wide range of functions, associated with apoptosis, cancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases.
5 mL Amber Glass Screw Cap Vial (810209P-1mg)
NONH for all modes of transport
Handbook of Glycosyltransferases and Related Genes, 5-5 (2011)
A role for ceramides, but not sphingomyelins, as antagonists of insulin signaling and mitochondrial metabolism in C2C12 myotubes
Park M, et al.
The Journal of Biological Chemistry, 291(46), 23978-23988 (2016)