810209P

Avanti

C6-NBD Ceramide

N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-D-erythro-sphingosine, powder

Empirical Formula (Hill Notation):
C30H49N5O6
CAS号:
分子量:
575.74
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810209P-1mg)

mfr. no.

Avanti Polar Lipids, 810209P

shipped in

dry ice

storage temp.

−20°C

General description

C6-NBD ceramide is a fluorescent labelled compound, known to be useful for the detection of enzymatic action. C6-NBD ceramide is preferred over radioactive compounds.

Application

C6-NBD Ceramide is suitable as a substrate for sphingomyelin synthase activity assay.

Biochem/physiol Actions

Ceramide is one of the products of sphingolipid metabolism. The members of ceramide synthases family are responsible for its synthesis. Each ceramide synthesized differs in its acyl chain length. Ceramides possess a wide range of functions, associated with apoptosis, cancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases.

Packaging

5 mL Amber Glass Screw Cap Vial (810209P-1mg)

RIDADR

NONH for all modes of transport

分析证书
原产地证书 (CofO)
Handbook of Glycosyltransferases and Related Genes, 5-5 (2011)
A role for ceramides, but not sphingomyelins, as antagonists of insulin signaling and mitochondrial metabolism in C2C12 myotubes
Park M, et al.
The Journal of Biological Chemistry, 291(46), 23978-23988 (2016)
Mammalian ceramide synthases
Levy M and Futerman AH
IUBMB Life, 62(5), 347-356 (2010)

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