810214C

Avanti

C6-NBD Phytosphingosine

N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-phytosphingosine, chloroform

Empirical Formula (Hill Notation):
C30H51N5O7
CAS号:
分子量:
593.76
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

packaging

pkg of 1 × 1 mL (810214C-50ug)

mfr. no.

Avanti Polar Lipids, 810214C

concentration

0.05 mg/mL (810214C-50ug)

shipped in

dry ice

storage temp.

−20°C

General description

C6-NBD Phytosphingosine is a fluorescent derivative of phytosphingosine (PHS). Its fluorescent property is due to presence of NBD (2-(4-nitro-2,1,3-benzoxadiazol-7-yl) aminoethyl) group.

Application

C6-NBD Phytosphingosine or N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-phytosphingosine is suitable for use in membrane fusion and verification studies using forster resonance energy transfer (FRET).

Biochem/physiol Actions

Phytosphingosine (PHS) is a long-chain base sphingoid and a major constituent of various phytoceramides. PHS is abundantly present in skin, intestine, and kidneys of animals. It exhibits anti-inflammatory and antimicrobial properties. PHS is known to increase the expression of genes including transglutaminase 1 and involucrin, that are involved in keratinocyte differentiation in humans.

Packaging

5 mL Amber Glass Screw Cap Vial (810214C-50ug)

RIDADR

UN 1888 6.1 / PGIII

分析证书
原产地证书 (CofO)
Fluorescent and Luminescent Probes for Biological Activity null
Endotoxin-adsorbing macrophage-mimetic hybrid liposome for sepsis treatment
Jiang LL, et al.
Chemical Engineering Journal, 371(1), 15-25 (2019)
Hyun Kyung Choi et al.
Archives of dermatological research, 309(10), 795-803 (2017-09-25)
Phytosphingosine (PHS) is a sphingoid that is a key component of phytoceramides NP, AP and EOP. PHS has been known to have anti-inflammation and antimicrobial activities and to stimulate epidermal differentiation. In addition, it is reported that PHS treatment notably...
Chunai Gong et al.
Journal of nanobiotechnology, 18(1), 92-92 (2020-06-18)
Cell membrane- covered drug-delivery nanoplatforms have been garnering attention because of their enhanced bio-interfacing capabilities that originate from source cells. In this top-down technique, nanoparticles (NPs) are covered by various membrane coatings, including membranes from specialized cells or hybrid membranes...

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门

社交媒体

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

Merck

科研、开发、生产。

作为生命科学行业的全球领先供应商,我们致力于为科研、生物技术开发和生产,以及制药药物疗法开发和生产提供各类解决方案和服务。

© 2021年版权归德国达姆施塔特默克集团(Merck KGaA)及/或其附属公司所有。版权所有。

未经许可,严禁复制本网站上的任何资料。