810225C

Avanti

18:1 Dansyl PS

1,2-dioleoyl-sn-glycero-3-phospho-L-serine-N-(5-dimethylamino-1-naphthalenesulfonyl) (ammonium salt), chloroform

Empirical Formula (Hill Notation):
C54H95N4O12PS
CAS号:
分子量:
1055.39
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

packaging

pkg of 1 × 1 mL (810225C-1mg)
pkg of 5 × 1 mL (810225C-5mg)

mfr. no.

Avanti Polar Lipids, 810225C

concentration

1 mg/mL (810225C-1mg)
1 mg/mL (810225C-5mg)

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylserine (PS), a glycerophospholipid, is found in the inner leaflet of the plasma membrane and in endocytic membranes. Dansyl ((dimethyl amino)naphthalene-1-sulfonYL) group produces blue or blue-green fluorescent adduct and thus can be used for various fluorescence based studies.

Application

18:1 Dansyl PS is suitable for preparation of liposomes for sedimentation assays and other fluorometric analysis like FRET.

Biochem/physiol Actions

Phosphatidylserine (PS) is an important cell cycle signaling molecule which contributes to the clearance of apoptotic cells. It is also known to trigger the blood coagulation process acting as a pro-coagulant surface.

Packaging

5 mL Amber Glass Screw Cap Vial (810225C-5mg)
5 mL Amber Glass Screw Cap Vial (810225C-1mg)

RIDADR

UN 1888 6.1 / PGIII

分析证书
原产地证书 (CofO)
Supplemental Data ESCRT-I Core and ESCRT-II GLUE Domain Structures Reveal Role for GLUE in Linking to ESCRT-I and Membranes
Advances in Planar Lipid Bilayers and Liposomes, 125(1), 99-111 (2011)
Laurent Meertens et al.
Cell host & microbe, 12(4), 544-557 (2012-10-23)
Dengue viruses (DVs) are responsible for the most medically relevant arboviral diseases. However, the molecular interactions mediating DV entry are poorly understood. We determined that TIM and TAM proteins, two receptor families that mediate the phosphatidylserine (PtdSer)-dependent phagocytic removal of...
Barry R Lentz
Progress in lipid research, 42(5), 423-438 (2003-06-20)
This article addresses the role of platelet membrane phosphatidylserine (PS) in regulating the production of thrombin, the central regulatory molecule of blood coagulation. PS is normally located on the cytoplasmic face of the resting platelet membrane but appears on the...
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly...

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