810286C

Avanti

TopFluor® Cardiolipin

1,1′,2,2′-tetraoleoyl cardiolipin4-(dipyrrometheneboron difluoride)butanoyl (ammonium salt) TopFluor® Cardiolipin, chloroform

别名:
1′,3′-bis1,2-dioleoyl-sn-glycero-3-phospho-2′-4-(dipyrrometheneboron difluoride) butanoyl-sn-glycerol (ammonium salt); TopFluor-CL
Empirical Formula (Hill Notation):
C98H175BF2N4O18P2
CAS号:
分子量:
1808.21
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

packaging

pkg of 1 × 1 mL (810286C-100ug)
pkg of 1 × 1 mL (810286C-500ug)

mfr. no.

Avanti Polar Lipids, 810286C

concentration

0.1 mg/mL (810286C-100ug)
0.5 mg/mL (810286C-500ug)

shipped in

dry ice

storage temp.

−20°C

General description

Cardiolipin, a unique phospholipid is present and synthesised in the inner mitochondrial membrane.
TopFluor® cardiolipin is a fluorescent analog of the bioactive phospholipid, cardiolipin.

Biochem/physiol Actions

Cardiolipin is very much essential for the functional activity of several inner mitochondrial membrane proteins, like respiratory chain complexes. It participates in mitochondrial oxidative phosphorylation. It is also essential for proper functioning and structure of the inner mitochondrial membrane (IMM).

Packaging

5 mL Amber Glass Screw Cap Vial (810286C-100ug)
5 mL Amber Glass Screw Cap Vial (810286C-500ug)

Legal Information

TopFluor is a registered trademark of Avanti Polar Lipids, Inc.

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Target Organs

Central nervous system

RIDADR

UN 1888 6.1 / PGIII

WGK Germany

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

分析证书
原产地证书 (CofO)
Clyde A Daly et al.
Langmuir : the ACS journal of surfaces and colloids, 36(18), 5030-5039 (2020-04-18)
The composition, orientation, and conformation of proteins in biomolecular coronas acquired by nanoparticles in biological media contribute to how they are identified by a cell. While numerous studies have investigated protein composition in biomolecular coronas, relatively little detail is known...
Functional role of cardiolipin in mitochondrial bioenergetics
Paradies G, et al.
Biochimica et Biophysica Acta - Bioenergetics, 1837(4), 408-417 (2014)
Cintia Kawai et al.
The journal of physical chemistry. B, 118(41), 11863-11872 (2014-09-24)
Fluorescence quenching of lipid-bound pyrene was used to assess the binding of cytochrome c (cyt c) to liposomes that mimic the inner mitochondrial membrane (IMM) POPC/DOPE/TOCL, with the conditions that it did or did not contain oxidized phosphatidylcholine molecules, i.e....

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