840045P

Avanti

脑 PI (4) P

L-α-phosphatidylinositol-4-phosphate (Brain, Porcine) (ammonium Salt), powder

CAS号:
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (840045P-1mg)
pkg of 1 × 10 mg (840045P-10mg)
pkg of 1 × 25 mg (840045P-25mg)
pkg of 1 × 5 mg (840045P-5mg)

mfr. no.

Avanti Polar Lipids, 840045P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP(O)([O-])=O)[C@@H](O)[C@H]1O)([O-])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+]

General description

磷脂酰肌醇4-磷酸酯(PI4P)是磷脂酰肌醇(4,5)-双磷酸酯[PI(4,5)P2]的前体。它存在于高尔基体的膜中。

Packaging

5 mL透明玻璃密封安瓿(840045P-25mg)
5 mL透明玻璃密封安瓿(840045P-1mg)
5 mL透明玻璃密封安瓿(840045P-10mg)
5 mL透明玻璃密封安瓿(840045P-5mg)

RIDADR

NONH for all modes of transport

PI4P and PI (4, 5) P2 are essential but independent lipid determinants of membrane identity
Hammond GRV, et al.
Science, 337(6095), 727-730 (2012)
Dieter R Klopfenstein et al.
Molecular biology of the cell, 15(8), 3729-3739 (2004-05-25)
UNC-104 (KIF1A) is a kinesin motor that transports synaptic vesicles from the neuronal cell body to the terminal. Previous in vitro studies have shown that a Dictyostelium relative of UNC-104 transports liposomes containing acidic phospholipids, but whether this interaction is...
Jitendra Kumar et al.
PLoS genetics, 6(11), e1001200-e1001200 (2010-11-17)
UNC-104/KIF1A is a Kinesin-3 motor that transports synaptic vesicles from the cell body towards the synapse by binding to PI(4,5)P(2) through its PH domain. The fate of the motor upon reaching the synapse is not known. We found that wild-type...
Dieter R Klopfenstein et al.
Cell, 109(3), 347-358 (2002-05-23)
Unc104 (KIF1A) kinesin transports membrane vesicles along microtubules in lower and higher eukaryotes. Using an in vitro motility assay, we show that Unc104 uses a lipid binding pleckstrin homology (PH) domain to dock onto membrane cargo. Through its PH domain...
Ricarda A Busse et al.
Autophagy, 9(5), 770-777 (2013-03-01)
We characterized phosphoinositide binding of the S. cerevisiae PROPPIN Hsv2 qualitatively with density flotation assays and quantitatively through isothermal titration calorimetry (ITC) measurements using liposomes. We discuss the design of these experiments and show with liposome flotation assays that Hsv2...

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