840886C

Avanti

20:4 PA

1,2-diarachidonoyl-sn-glycero-3-phosphate (sodium salt), chloroform

别名:
1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate (sodium salt); DAPA; PA(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z))
Empirical Formula (Hill Notation):
C43H68O8PNa
CAS号:
分子量:
766.96
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

packaging

pkg of 1 × 2.5 mL (840886C-25mg)
pkg of 2 × 4 mL (840886C-200mg)

mfr. no.

Avanti Polar Lipids, 840886C

concentration

10 mg/mL (840886C-25mg)
25 mg/mL (840886C-200mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O.[Na+]

General description

Phosphatidic acid (PA) is a precursor of lysophosphatidic acid (LPA) and is present in leafy vegetables. 20:4 PA or 1,2-diarachidonoyl-sn-glycero-3-phosphate (sodium salt) is a sodium salt of phosphatidic acid, with substitution of two chains of arachidonic acid at the sn-1 and sn-2 positions, in the glycerol backbone.

Application

20:4 PA or 1,2-diarachidonoyl-sn-glycero-3-phosphate (sodium salt) has been used as a supplement in mouse chow to see changes in small intestine gene expression.

Packaging

5 mL Clear Glass Sealed Ampule (840886C-200mg)
5 mL Clear Glass Sealed Ampule (840886C-25mg)

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Target Organs

Central nervous system

RIDADR

UN 1888 6.1 / PGIII

WGK Germany

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Mohamad Navab et al.
Journal of lipid research, 54(12), 3403-3418 (2013-10-03)
We recently reported that levels of unsaturated lysophosphatidic acid (LPA) in the small intestine significantly correlated with the extent of aortic atherosclerosis in LDL receptor-null (LDLR⁻/⁻) mice fed a Western diet (WD). Here we demonstrate that WD increases unsaturated (but...

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