841118C

Avanti

Egg Trans PE

L-α-phosphatidylethanolamine, transphosphatidylated (Egg, Chicken), chloroform

别名:
L-a-Phosphatidylethanolamine Transphosphatidylated (prepared from Egg PC)
CAS号:
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

packaging

pkg of 1 × 2.5 mL (841118C-25mg)

mfr. no.

Avanti Polar Lipids, 841118C

concentration

10 mg/mL (841118C-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O

General description

Phosphatidylethanolamine (PE) is a phospholipid found in all living organism. The egg yolk contains high levels of unsaturated PE which accounts to 83.10%. The phosphatidylethanolamine (PE) headgroup is a zwitterion, with a negatively charged phosphate group and positively charged free amine group.

Application

Egg Trans PE is suitable for use:
  • in the incubation of platelets for phospholipid enrichment and quantification by ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS)
  • in the synthesis of isoketals-phosphatidylethanolamine (IsoK-PE)
  • in the preparation of phospholipid vesicles for factor X activation studies

Biochem/physiol Actions

Phosphatidylethanolamine (PE) along with other phospholipids forms the backbone of biological membranes. PE is known to regulate autophagy. The autophagic membranes possesses PE with high degree of unsaturation. Egg yolk PE has high radical scavenging activity owing to antioxidant potential.

Packaging

5 mL Clear Glass Sealed Ampule (841118C-25mg)

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Target Organs

Central nervous system

RIDADR

UN 1888 6.1 / PGIII

WGK Germany

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Analytical characterization of the role of phospholipids in platelet adhesion and secretion
Koseoglu S, et al.
Analytical Chemistry, 87(1), 413-421 (2014)
Isoketals form cytotoxic phosphatidylethanolamine adducts in cells
Sullivan CB, et al.
Journal of Lipid Research, 51(5), 999-1009 (2010)
Factor VIII C1 domain spikes 2092-2093 and 2158-2159 comprise regions that modulate cofactor function and cellular uptake
Bloem E, et al.
Journal of biological and chemical chronicles, 288(41), 29670-29679 (2013)
The
The Membranes of Cells, 22(3) (2016)
C Blake Sullivan et al.
Journal of lipid research, 51(5), 999-1009 (2009-12-08)
Levuglandins and their stereo- and regio-isomers (termed isolevuglandins or isoketals) are gamma-ketoaldehydes (IsoK) that rapidly react with lysines to form stable protein adducts. IsoK protein adduct levels increase in several pathological conditions including cardiovascular disease. IsoKs can induce ion channel...

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