860060P

Avanti

Ganglioside GD3 (Bovine Milk)

GD3 Ganglioside (Milk, Bovine-Ammonium Salt), powder

别名:
110954
CAS号:
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (860060P-1mg)
pkg of 1 × 5 mg (860060P-5mg)

mfr. no.

Avanti Polar Lipids, 860060P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)CO[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H]([C@H](O[C@@]3(C([O-])=O)O[C@@H]([C@H](O)[C@H](O)CO[C@@]4(C([O-])=O)O[C@@H]([C@H](O)[C@H](O)CO)[C@@](NC(C)=O)([H])[C@@H](O)C4)[C@@](NC(

General description

Gangliosides are glycosphingolipids containing a hydrophobic ceramide and hydrophilic oligosaccharide chain. They are found in various tissues and fluids in vertebrates, especially in human brain and bovine milk. The most common gangliosides in milk are 2NeuAc−2Hex−Cer (GD3) and NeuAc−2Hex−Cer (GM3).

Application

Ganglioside GD3 (Bovine Milk) is suitable as a lipid standard in Fourier-transform ion cyclotron resonance (FTICR) mass spectrometric analysis and liquid chromatography−mass spectrometry (LC-MS/MS) data analysis.

Biochem/physiol Actions

Gangliosides are involved in neuronal development, neuropathologic processes, receptor interactions with protein hormones, interferon, fibronectin and toxins from bacteria, They are also essential for the development of intestinal immunity by producing intestinal IgA and cytokine.

Packaging

5 mL Amber Glass Screw Cap Vial (860060P-1mg)
5 mL Amber Glass Screw Cap Vial (860060P-5mg)

RIDADR

NONH for all modes of transport

Combination of ESI and MALDI mass spectrometry for qualitative, semi-quantitative and in situ analysis of gangliosides in brain
Zhang Y, et al.
Scientific Reports, 6, 25289-25289 (2016)
Rapid profiling of bovine and human milk gangliosides by matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry
Lee H, et al.
International Journal of Mass Spectrometry, 305(2-3), 138-150 (2011)
Intact glycosphingolipidomic analysis of the cell membrane during differentiation yields extensive glycan and lipid changes
Wong M, et al.
Scientific reports, 8(1), 10993-10993 (2018)
Variation of the ganglioside compositions of human milk, cow?s milk and infant formulas
Pan X L, et al.
Early Human Development, 57(1), 25-31 (2000)
The role of dietary gangliosides on immunity and the prevention of infection
Rueda R
The British Journal of Nutrition, 98(S1), S68-S73 (2007)

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门

社交媒体

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

Merck

科研、开发、生产。

作为生命科学行业的全球领先供应商,我们致力于为科研、生物技术开发和生产,以及制药药物疗法开发和生产提供各类解决方案和服务。

© 2021年版权归德国达姆施塔特默克集团(Merck KGaA)及/或其附属公司所有。版权所有。

未经许可,严禁复制本网站上的任何资料。