860203C

Avanti

18:1 Phosphatidylbutanol

1,2-dioleoyl-sn-glycero-3-phosphobutanol (sodium salt), chloroform

别名:
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphobutanol (sodium salt)
Empirical Formula (Hill Notation):
C43H80O8PNa
CAS号:
分子量:
779.05
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

packaging

pkg of 1 × 2.5 mL (860203C-25mg)

mfr. no.

Avanti Polar Lipids, 860203C

concentration

10 mg/mL (860203C-25mg)

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylbutanol is a low polarity phosphatidylalcohol. This phospholipid is synthesized by the phospholipase D (PLD) catalyzed transphosphatidylation reaction of phosphatidylcholine (PC) and butanol.

Application

18:1 Phosphatidylbutanol or 1,2-dioleoyl-sn-glycero-3-phosphobutanol (sodium salt) has been used as a standard to measure phospholipase D (PLD) activity in smooth muscle cells (SMCs) and cancer cell lines by thin layer-chromatography.

Biochem/physiol Actions

Phosphatidylbutanol is used in phospholipase D activity assays as a potential biomarker.

Packaging

5 mL Clear Glass Sealed Ampule (860203C-25mg)

RIDADR

UN 1888 6.1 / PGIII

Elyssa Bernfeld et al.
The Journal of biological chemistry, 293(42), 16390-16401 (2018-09-09)
Glutamine is a key nutrient required for sustaining cell proliferation, contributing to nucleotide, protein, and lipid synthesis. The mTOR complex 1 (mTORC1) is a highly conserved protein complex that acts as a sensor of nutrients, relaying signals for the shift...
Y Liu et al.
American journal of physiology. Lung cellular and molecular physiology, 295(3), L471-L478 (2008-07-16)
We have previously reported the participation of mitogen-activated protein, Rho, and phosphoinositide-3 (PI3) kinases in separate pathways in serotonin (5-HT)-induced proliferation of pulmonary artery smooth muscle cells (SMCs). In this study, we investigated the possible participation of phospholipase D (PLD)...
Maria A Frias et al.
The Journal of biological chemistry, 295(1), 263-274 (2019-11-27)
Mammalian target of rapamycin complex 1 (mTORC1) promotes cell growth and proliferation in response to nutrients and growth factors. Amino acids induce lysosomal translocation of mTORC1 via the Rag GTPases. Growth factors activate Ras homolog enriched in brain (Rheb), which...
Mikhail Vyssotski et al.
Lipids, 44(4), 381-389 (2008-12-17)
High-performance TLC and (31)P-NMR were assessed as methods of observing the presence of numerous low polarity phospholipids: bis-phosphatidic acid (BPA), semi-lyso bis-phosphatidic acid (SLBPA), N-acyl phosphatidylethanolamine (NAPE), N-(1,1-dimethyl-3-oxo-butyl)-phosphatidylethanolamine (diacetone adduct of PE, DOBPE), N-acetyl PE, phosphatidylmethanol (PM), phosphatidylethanol (PEt), phosphatidyl-n-propanol...

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门

社交媒体

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

Merck

科研、开发、生产。

作为生命科学行业的全球领先供应商,我们致力于为科研、生物技术开发和生产,以及制药药物疗法开发和生产提供各类解决方案和服务。

© 2021年版权归德国达姆施塔特默克集团(Merck KGaA)及/或其附属公司所有。版权所有。

未经许可,严禁复制本网站上的任何资料。