860457P

Avanti

N-C24:1-deoxysphingosine

N-nervonoyl-1-deoxysphingosine (m18:1/24:1), powder

别名:
N-(15Z-tetracosenoyl)-1-deoxysphing-4-enine (m18:1/24:1); N-C24:1-1-deoxyCer; 110996
Empirical Formula (Hill Notation):
C42H81NO2
CAS号:
分子量:
632.10
NACRES:
NA.25
价格与库存信息目前不能提供

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (860457P-1mg)

mfr. no.

Avanti Polar Lipids, 860457P

shipped in

dry ice

storage temp.

−20°C

General description

The sphingoid bases sphingosine is acylated with fatty acids with varying acyl-chain resulting in the synthesis of 1-deoxydihydroceramides (1-deoxyDHCers). These deoxyDHCers are further converted to 1-deoxyceramides (1-deoxysphingosine) and 1-(deoxymethyl)ceramides. They are produced by mammals.

Biochem/physiol Actions

The 1-deoxydihydroceramides are hydrophobic and interact with monolayers and giant unilamellar vesicles. They modulate cell membrane and may affect their biological functionality.

Packaging

5 mL Amber Glass Screw Cap Vial (860457P-1mg)

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Biophysical properties of novel 1-deoxy-(dihydro) ceramides occurring in mammalian cells
Jimenez-Rojo N, et al.
Biophysical Journal, 107(12), 2850-2859 (2014)
Sarah T Pruett et al.
Journal of lipid research, 49(8), 1621-1639 (2008-05-24)
"Sphingosin" was first described by J. L. W. Thudichum in 1884 and structurally characterized as 2S,3R,4E-2-aminooctadec-4-ene-1,3-diol in 1947 by Herb Carter, who also proposed the designation of "lipides derived from sphingosine as sphingolipides." This category of amino alcohols is now...

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门

社交媒体

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

Merck

科研、开发、生产。

作为生命科学行业的全球领先供应商,我们致力于为科研、生物技术开发和生产,以及制药药物疗法开发和生产提供各类解决方案和服务。

© 2021年版权归德国达姆施塔特默克集团(Merck KGaA)及/或其附属公司所有。版权所有。

未经许可,严禁复制本网站上的任何资料。