860640P

Avanti

Sphingosine (d17:1)

D-erythro-sphingosine (C17 base), powder

Empirical Formula (Hill Notation):
C17H35NO2
CAS号:
分子量:
285.47
NACRES:
NA.25
价格与库存信息目前不能提供

form

powder

packaging

pkg of 1 × 10 mg (860640P-10mg)
pkg of 1 × 5 mg (860640P-5mg)

mfr. no.

Avanti Polar Lipids, 860640P

shipped in

dry ice

storage temp.

−20°C

SMILES string

OCC@@(N)(H)C@(H)(O)/C=C/CCCCCCCCCCCC

General description

Sphingosine (d17:1) or D-erythro-sphingosine is a 17-carbon sphingolipid, found in human skin. It has one carbon less than naturally occurring C18-sphingosine.

Application

Sphingosine (d17:1) has been used as a lipid standard in the analysis of sphingolipids by liquid chromatography-mass spectrometry (LC-MS) and tandem mass spectrometry.

Biochem/physiol Actions

Sphingosine acts a precursor for sphingosine-1-phosphate (S1P). Sphingosine C-17 is used as an internal standard in the analysis of sphingolipids by spectrometric methods.

Packaging

5 mL Amber Glass Screw Cap Vial (860640P-5mg)
5 mL Amber Glass Screw Cap Vial (860640P-10mg)

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6
Schull S, et al.
Cell Death & Disease, 6(3), e1691-e1691 (2015)
Free sphingosines of human skin include 6-hydroxysphingosine and unusually long-chain dihydrosphingosines
Stewart ME and Downing DT
The Journal of Investigative Dermatology, 105(4), 613-618 (1995)
A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia
Paugh SW, et al.
Blood, 112(4), 1382-1391 (2008)
Guang-Yi Dai et al.
The Journal of biological chemistry, 295(3), 717-728 (2019-12-11)
Cellular membranes contain many lipids, some of which, such as sphingolipids, have important structural and signaling functions. The common sphingolipid glucosylceramide (GlcCer) is present in plants, fungi, and animals. As a major plant sphingolipid, GlcCer is involved in the formation...
Evaluation of bioactive sphingolipids in 4-HPR-resistant leukemia cells
Apraiz A, et al.
BMC Cancer, 11(1), 477-477 (2011)

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门

社交媒体

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

Merck

科研、开发、生产。

作为生命科学行业的全球领先供应商,我们致力于为科研、生物技术开发和生产,以及制药药物疗法开发和生产提供各类解决方案和服务。

© 2021年版权归德国达姆施塔特默克集团(Merck KGaA)及/或其附属公司所有。版权所有。

未经许可,严禁复制本网站上的任何资料。