860647P

Avanti

C18:1 Ceramide (d17:1/18:1(9Z))

N-oleoyl-D-erythro-sphingosine (C17 base), powder

Empirical Formula (Hill Notation):
C35H67NO3
CAS号:
分子量:
549.91
NACRES:
NA.25
价格与库存信息目前不能提供

form

powder

packaging

pkg of 1 × 10 mg (860647P-10mg)

mfr. no.

Avanti Polar Lipids, 860647P

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCC/C=C\CCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCC

General description

C18:1 Ceramide (d17:1/18:1(9Z)) is a synthetic ceramide containing C17 analog of sphingosine with oleic acid. It is the key component of cell membranes.

Application

C18:1 Ceramide (d17:1/18:1(9Z)) has been used as an internal standard to quantify ceramides in muscles by Agilent 6460 triple quadrupole mass spectrometry.

Biochem/physiol Actions

Ceramides acts as a precursor for various sphingolipids. Ceramides play an important role in cell differentiation, proliferation, and apoptosis. In addition, it also acts as a secondary transmitter in cell signaling. C18 species of ceramide is particularly involved in cell growth inhibition.

Packaging

5 mL Amber Glass Screw Cap Vial (860647P-10mg)

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available

Yang Wang et al.
The Journal of nutritional biochemistry, 64, 182-197 (2018-12-12)
Metabolic syndrome components, including obesity, dyslipidemia and impaired glucose homeostasis, become a major public health issue. Muscles play a predominant role in insulin-mediated glucose uptake, and high fat diets may negatively affect muscle function and homeostasis. This work aimed to...
Takhar Kasumov et al.
Analytical biochemistry, 401(1), 154-161 (2010-02-25)
We present an optimized and validated liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) method for the simultaneous measurement of concentrations of different ceramide species in biological samples. The method of analysis of tissue samples is based on Bligh and...
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the...
Luisa Coderch et al.
American journal of clinical dermatology, 4(2), 107-129 (2003-01-30)
Ceramides are the major lipid constituent of lamellar sheets present in the intercellular spaces of the stratum corneum. These lamellar sheets are thought to provide the barrier property of the epidermis. It is generally accepted that the intercellular lipid domain...
Anna Zalewska et al.
Biomolecules, 9(12) (2019-12-19)
This is the first study to investigate the relationship between ceramides, the mitochondrial respiratory system, oxidative stress, inflammation, and apoptosis in the submandibular gland mitochondria of mice with insulin resistance (IR). The experiment was conducted on 20 male C57BL/6 mice...

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门

社交媒体

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

Merck

科研、开发、生产。

作为生命科学行业的全球领先供应商,我们致力于为科研、生物技术开发和生产,以及制药药物疗法开发和生产提供各类解决方案和服务。

© 2021年版权归德国达姆施塔特默克集团(Merck KGaA)及/或其附属公司所有。版权所有。

未经许可,严禁复制本网站上的任何资料。