860648P

Avanti

C20 Ceramide (d17:1/20:0)

N-arachidoyl-D-erythro-sphingosine (C17 base), powder

Empirical Formula (Hill Notation):
C37H73NO3
CAS号:
分子量:
579.98
NACRES:
NA.25
价格与库存信息目前不能提供

form

powder

packaging

pkg of 1 × 10 mg (860648P-10mg)

mfr. no.

Avanti Polar Lipids, 860648P

shipped in

dry ice

storage temp.

−20°C

SMILES string

OCC@(H)(NC(CCCCCCCCCCCCCCCCCCC)=O)C@(H)(O)/C=C/CCCCCCCCCCCC

General description

C20 Ceramide (d17:1/20:0) is a synthetic ceramide containing C17 analog of sphingosine with arachidonic acid. Ceramide synthase 2 catalyzes the synthesis of C20 Ceramide. Ceramide is the key component of sphingolipids.

Application

C20 Ceramide (d17:1/20:0) has been used as an internal standard to measure the sphingolipid content in liver by ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC/MS/MS).

Biochem/physiol Actions

Ceramides play an important role in cell signaling, cell differentiation, proliferation and apoptosis.

Packaging

5 mL Amber Glass Screw Cap Vial (860648P-10mg)

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available

Ceramide Structure and Derivatives
Kumari A
Sweet Biochemistry: Remembering Structures, Cycles, and Pathways by Mnemonics (2018)
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the...
Luisa Coderch et al.
American journal of clinical dermatology, 4(2), 107-129 (2003-01-30)
Ceramides are the major lipid constituent of lamellar sheets present in the intercellular spaces of the stratum corneum. These lamellar sheets are thought to provide the barrier property of the epidermis. It is generally accepted that the intercellular lipid domain...
Ling Chen et al.
Oncology reports, 34(1), 447-454 (2015-05-16)
Endocannabinoids and ceramides have demonstrated growth inhibition, cell death induction and pro-apoptotic activity in cancer research. In the present study, we describe the profiles of two major endocannabinoids, ceramides, free fatty acids and relevant metabolic enzymes in 47 pairs of...

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