860655P

Avanti

sphinganine-1-phosphate (d17:0)

D-erythro-sphinganine-1-phosphate (C17 base), powder

Empirical Formula (Hill Notation):
C17H38NO5P
CAS号:
分子量:
367.46
NACRES:
NA.25
价格与库存信息目前不能提供

form

powder

packaging

pkg of 1 × 1 mg (860655P-1mg)

mfr. no.

Avanti Polar Lipids, 860655P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](CCCCCCCCCCCCCC)(O)[C@]([NH3+])([H])COP([O-])(O)=O

Application

Sphinganine-1-phosphate (d17:0) has been used as an internal standard in mass spectroscopy for quantification of shingolipids.

Biochem/physiol Actions

Exogenous sphinganine 1-phosphate activates sphingosine-1-phosphate receptor 1 (S1P1) and exhibits protective effects against hepatic and renal ischemia and reperfusion (IR).

Packaging

5 mL Amber Glass Screw Cap Vial (860655P-1mg)

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Ladan Dawoody Nejad et al.
Scientific reports, 10(1), 8268-8268 (2020-05-20)
Sphingosine-1-phosphate is a signaling molecule involved in the control of cell migration, differentiation, survival and other physiological processes. This sphingolipid metabolite can be degraded by the action of sphingosine-1-phosphate lyase (SPL) to form hexadecenal and ethanolamine phosphate. The importance of...
Sphinganine-1-phosphate protects kidney and liver after hepatic ischemia and reperfusion in mice through S1P 1 receptor activation
Park SW, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 90(8), 1209-1209 (2010)
TP53 is required for BECN1-and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition
Lim S, et al.
Autophagy, 14(6), 942-957 (2018)

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