870013C

Avanti

16:0 MPB PE

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidophenyl)butyramide] (sodium salt), chloroform

Empirical Formula (Hill Notation):
C51H84N2O11PNa
CAS号:
分子量:
955.18
NACRES:
NA.25
价格与库存信息目前不能提供

packaging

pkg of 1 × 2.5 mL (870013C-25mg)

mfr. no.

Avanti Polar Lipids, 870013C

concentration

10 mg/mL (870013C-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(CCCC(C=C1)=CC=C1N(C(C=C2)=O)C2=O)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

General description

Maleimidophenyl butyramide (MPB) phosphoethanolamine (PE) also known as, DPPE-maleimide contains maleimide, which is a thiol-reactive moiety and a good electrophile. MPB PE is implicated in liposome preparation.

Application

16:0 maleimidophenyl butyramide (MPB) phosphoethanolamine (PE) is suitable for use in preparation of liposomes by the film hydration technique.
16:0 MPB PE has been used:
  • for covalent coupling of monoclonal antibody
  • in the lipidation of C-terminal cysteine thiol of ligand binding site-1 (LBS-1)
  • to conjugate with peptides for incorporation into liposomes, which were then used in the surface plasmon resonance (SPR)-based binding experiments

Packaging

5 mL Clear Glass Sealed Ampule (870013C-25mg)

RIDADR

UN 1888 6.1 / PGIII

Computed tomography in color: NanoK-enhanced spectral CT molecular imaging
Pan D, et al.
Angewandte Chemie (International ed. in English), 49(50), 9635-9639 (2010)
Stabilization of liposomes through enzymatic polymerization of DNA
Ruysschaert T, et al.
Nano Letters, 6(12), 2755-2757 (2006)
A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex
Kelly BT, et al.
Nature, 456(7224), 976-976 (2008)
Liposomes as tools in basic research and industry (1994)
Structural basis for thrombin activation of a protease-activated receptor: inhibition of intramolecular liganding
Seeley S, et al.
Chemistry & Biology, 10(11), 1033-1041 (2003)

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