870128P

Avanti

16:0 DBCO PE

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-dibenzocyclooctyl, powder

Empirical Formula (Hill Notation):
C56H90N3O10P
CAS号:
分子量:
996.30
NACRES:
NA.25
价格与库存信息目前不能提供

form

powder

packaging

pkg of 1 × 25 mg (870128P-25mg)

mfr. no.

Avanti Polar Lipids, 870128P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(CCC(N1CC(C=CC=C2)=C2C#CC3=C1C=CC=C3)=O)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]

General description

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-dibenzocyclooctyl (16:0 DBCO PE) is a head group modified lipid containing dibenzocyclooctyne (DBCO). It is a widely used reagent in click chemistry.

Application

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-dibenzocyclooctyl (16:0 DBCO PE or DPPE-DBCO) has been used in preparation of DBCO-presenting lipid bilayers. It has also been used in preparation of clickable cubosomes for antibody-free drug targeting and imaging applications.

Packaging

5 mL Amber Glass Screw Cap Vial (870128P-25mg)

RIDADR

NONH for all modes of transport

Flash Point(F)

No data available

Flash Point(C)

No data available

Nicolas Alcaraz et al.
Bioconjugate chemistry, 29(1), 149-157 (2017-11-29)
The combination of copper-free click chemistry with metabolic labeling offers new opportunities in drug delivery. The objective of this study was to determine whether cubosomes functionalized with azide or dibenzocyclooctyne (DBCO) groups are able to undergo copper-free click chemistry with...
Simon Finn Mayer et al.
Biochimica et biophysica acta. Biomembranes, 1861(10), 183023-183023 (2019-07-22)
Pore-forming antimicrobial peptides (AMPs) are attracting interest as cytolytic antibiotics and drug delivery agents with potential use for targeting cancer cells or multidrug-resistant pathogens. Ceratotoxin A (CtxA) is an insect-derived cytolytic AMP with 36 amino acids that is thought to...

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