870205C

Avanti

16:0 PDP PE

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio)propionate] (sodium salt), chloroform

Empirical Formula (Hill Notation):
C45H80N2O9PNaS2
CAS号:
分子量:
911.22
NACRES:
NA.25
价格与库存信息目前不能提供

packaging

pkg of 1 × 2.5 mL (870205C-25mg)

mfr. no.

Avanti Polar Lipids, 870205C

concentration

10 mg/mL (870205C-25mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(CCSSC1=CC=CC=N1)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

General description

16:0 PDP PE, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[3-(2-pyridyldithio) propionate, is a head group modified functionalized lipid. Functionalized lipids mainly act as reporting molecules.

Application

16:0 PDP PE has been used to synthesize high-density lipoprotein (HDL)-like nano particles.
16:0 PDP PE has been used as an inner lipid to synthesizehigh density lipoprotein-like nanoparticles (HDL-like NPs).

Packaging

5 mL Clear Glass Sealed Ampule (870205C-25mg)

RIDADR

UN 1888 6.1 / PGIII

Synthetic high-density lipoprotein-like nanoparticles potently inhibit cell signaling and production of inflammatory mediators induced by lipopolysaccharide binding Toll-like receptor 4
Foit L and Thaxton CS
Biomaterials, 100, 67-75 (2016)
Linda Foit et al.
Biomaterials, 100, 67-75 (2016-06-01)
Toll-like receptor 4 (TLR4) plays a critical role in the innate immune system. Stimulation of TLR4 occurs upon binding lipopolysaccharide (LPS), a component of Gram-negative bacterial cell walls. Due to the potency of the induced inflammatory response, there is a...
Synthetic high-density lipoprotein-like nanoparticles potently inhibit cell signaling and production of inflammatory mediators induced by lipopolysaccharide binding Toll-like receptor 4
Foit L and Thaxton CS
Biomaterials, 100, 67-75 (2016)
Functionalized lipids and surfactants for specific applications
Kepczynski M and Rog T
Biochimica et Biophysica Acta - Biomembranes, 1858(10), 2362-2379 (2016)
Nicholas L Angeloni et al.
Scientific reports, 6, 22915-22915 (2016-03-12)
Exosomes are produced by cells to mediate intercellular communication, and have been shown to perpetuate diseases, including cancer. New tools are needed to understand exosome biology, detect exosomes from specific cell types in complex biological media, and to modify exosomes....

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