870225P

Avanti

16:0 Succinyl PE

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl) (sodium salt), powder

Empirical Formula (Hill Notation):
C41H77NO11PNa
CAS号:
分子量:
814.01
NACRES:
NA.25
价格与库存信息目前不能提供

form

powder

packaging

pkg of 1 × 25 mg (870225P-25mg)
pkg of 1 × 500 mg (870225P-500mg)

mfr. no.

Avanti Polar Lipids, 870225P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCN([H])C(CCC(O)=O)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

General description

16:0 Succinyl PE, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl)(DPPE), is a head group modified functionalized lipid. Functionalized lipids act as reporter molecules.

Biochem/physiol Actions

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl) (DPPE) is used in production of PHEA-EDA-DPPE-GAL copolymer. This copolymer is used in preparation of ribavirin (RBV) tripalmitate-loaded nanoparticles, that act as hepatic cell-targeted carriers for hepatitis C treatment.

Packaging

20 mL Clear Glass Screw Cap Vial (870225P-500mg)
5 mL Amber Glass Screw Cap Vial (870225P-25mg)

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Emanuela Fabiola Craparo et al.
Journal of biomedical nanotechnology, 9(6), 1107-1122 (2013-07-19)
In this paper, we describe the preparation of liver-targeted nanoparticles potentially able to carry to hepatocytes a ribavirin (RBV) prodrug, exploiting the presence of carbohydrate receptors in the liver (i.e., ASGPR in hepatocytes). These particles were obtained starting from a...
Mariusz Kepczynski et al.
Biochimica et biophysica acta, 1858(10), 2362-2379 (2016-03-08)
Synthetic lipids and surfactants that do not exist in biological systems have been used for the last few decades in both basic and applied science. The most notable applications for synthetic lipids and surfactants are drug delivery, gene transfection, as...

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