870704P

Avanti

辅酶 A,04:0

butanoyl Coenzyme A (sodium salt), powder

Empirical Formula (Hill Notation):
C25H39N7Na3O17P3S
CAS号:
分子量:
903.57
NACRES:
NA.25
价格与库存信息目前不能提供

form

powder

packaging

pkg of 1 × 5 mg (870704P-5mg)

mfr. no.

Avanti Polar Lipids, 870704P

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC@@(C(NCCC(NCCSC(CCC)=O)=O)=O)(C(C)(COP(O-)(OP(O-)(OCC@H(C@H1OP(O-)(O)=O)OC@H(C@@H1O)N2C3=C(C(N)=NC=N3)N=C2)=O)=O)C)H.Na+.Na+.Na+

General description

04:0 Coenzyme A, also known as butanoyl coenzyme A, is a coenzyme A derivative of butanoic acid. 04:0 Coenzyme A is a short-chain acyl CoA and is an intermediate of fatty acid degradation.

Biochem/physiol Actions

04:0 Coenzyme A acts as a source of N-acyl chain in the synthesis of N-butanoyl-L-homoserine lactone (BHL) by LuxI homologue RhlI (VsmI). Butanoyl coenzyme A serves as an intermediate in the synthesis of butyrate, which is involved in maintaining colonic homeostasis and gut health. It also has an ability to inhibit citrate synthase (CS). 

Packaging

5 mL Amber Glass Screw Cap Vial (870704P-5mg)

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Julian Trachsel et al.
Applied and environmental microbiology, 82(22), 6788-6798 (2016-10-30)
Studying the host-associated butyrate-producing bacterial community is important, because butyrate is essential for colonic homeostasis and gut health. Previous research has identified the butyryl coenzyme A (CoA):acetate-CoA transferase (EC 2.3.8.3) as a gene of primary importance for butyrate production in...
J C Lai et al.
Research communications in chemical pathology and pharmacology, 82(3), 331-338 (1993-12-01)
We investigated the hypothesis that one mechanism underlying fatty acid toxicity is the selective inhibition of rate-limiting and/or regulated tricarboxylic acid cycle and related enzymes by fatty acyl coenzyme A (CoA) derivatives by examining the effects of several fatty acyl...
Y Jiang et al.
Molecular microbiology, 28(1), 193-203 (1998-05-21)
In Pseudomonas aeruginosa, synthesis of the quorum-sensing signal molecules N-butanoyl-L-homoserine lactone (BHL) and N-hexanoyl-L-homoserine lactone (HHL) requires the Luxl homologue Rhll(Vsml). By using thin-layer chromatography in conjunction with high-performance liquid chromatography (HPLC) and mass spectrometry, we show that purified Rhll...

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