870852P

Avanti

C18:1(Δ9-cis) Carnitine

oleoyl L-carnitine, powder

Empirical Formula (Hill Notation):
C25H47NO4
CAS号:
分子量:
425.64
NACRES:
NA.25
价格与库存信息目前不能提供

form

powder

packaging

pkg of 1 × 5 mg (870852P-5mg)

mfr. no.

Avanti Polar Lipids, 870852P

shipped in

dry ice

storage temp.

−20°C

SMILES string

CN+(C)(C)CC@H(OC(CCCCCCC/C=C\CCCCCCCC)=O)CC(O-)=O

InChI

1S/C25H47NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-25(29)30-23(21-24(27)28)22-26(2,3)4/h12-13,23H,5-11,14-22H2,1-4H3/b13-12-

InChI key

IPOLTUVFXFHAHI-SEYXRHQNSA-N

Application

C18:1(Δ9-cis) Carnitine may be used as an internal standard to measure the levels of carnitines in plasma samples by tandem mass spectrometry (MS/MS).

Biochem/physiol Actions

C18:1(Δ9-cis) Carnitine or oleoyl L-carnitine, is an endogenous acylcarnitine. It is a potential non-competitive inhibitor of glycine transporter 2 (GLYT2). Oleoyl L-carnitine is used as an effective therapeutic for treating pain.

Packaging

5 mL Clear Glass Sealed Ampule (870852P-5mg)

RIDADR

NONH for all modes of transport

J E Carland et al.
British journal of pharmacology, 168(4), 891-902 (2012-09-18)
Concentrations of extracellular glycine in the CNS are regulated by two Na(+)/Cl(-) -dependent glycine transporters, GlyT1 and GlyT2. Selective inhibitors of GlyT1 have been developed for the treatment of schizophrenia, whilst selective inhibitors of GlyT2 are analgesic in animal models...
Lawrence C Johnson et al.
Clinical science (London, England : 1979), 132(16), 1765-1777 (2018-06-20)
Advancing age is associated with impairments in numerous physiological systems, leading to an increased risk of chronic disease and disability, and reduced healthspan (the period of high functioning healthy life). The plasma metabolome is thought to reflect changes in the...

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