18:0 PEG2000 PE

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt), chloroform



pkg of 1 × 2.5 mL (880120C-25mg)
pkg of 1 × 20 mL (880120C-500mg)
pkg of 2 × 4 mL (880120C-200mg)

mfr. no.

Avanti Polar Lipids, 880120C


10 mg/mL (880120C-25mg)
25 mg/mL (880120C-200mg)
25 mg/mL (880120C-500mg)

shipped in

dry ice

storage temp.


SMILES string


General description

18:0 PEG2000 PE, also known as 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000], is a modified phospholipid containing a 2000-Da PEG moiety in the polar head.


1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium salt (DSPE-PEG1) has been used to conjugate PEG onto residual amine groups on the surfaces of the functionalized TaO nanoparticles. DSPE-PEG1 may be used as a surfactant for homeotropic anchoring of the mesogen molecules. It may also be used in preparation of Nano formulations.

Biochem/physiol Actions

PEG-modified lipids are typically added to phospholipid vesicles used for drug delivery to facilitate the formation of sterically stabilized liposomes (SSL). These liposomes have low reticuloendothelial system (RES) uptake and they prolong the circulating plasma half-life of the drug. The plasma half-life of the drug can be tuned from several hours to days depending on the size of the PEG and fatty acids attached to the lipid anchor.


5 mL Clear Glass Sealed Ampule (880120C-200mg)
5 mL Clear Glass Sealed Ampule (880120C-25mg)
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (880120C-500mg)


Skull and crossbonesHealth hazard

Signal Word


Target Organs

Central nervous system


UN 1888 6.1 / PGIII

WGK Germany


Flash Point(F)

does not flash

Flash Point(C)

does not flash

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Liposomes with detachable polymer coating: destabilization and fusion of dioleoylphosphatidylethanolamine vesicles triggered by cleavage of surface-grafted poly (ethylene glycol)
Kirpotin D, et al.
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P A Melnikov et al.
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