880121C

Avanti

DSPE-PEG (2000)琥珀酰

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[succinyl(polyethylene glycol)-2000] (ammonium salt), chloroform

CAS号:
NACRES:
NA.25
价格与库存信息目前不能提供

packaging

pkg of 1 × 1 mL (880121C-10mg)

mfr. no.

Avanti Polar Lipids, 880121C

concentration

10 mg/mL (880121C-10mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO/C=C\N([H])C(CCC(O)=O)=O)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=

General description

DSPE-PEG(2000) Succinyl or 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[succinyl(polyethylene glycol)-2000] is a functionalized PEG lipid.
DSPE-PEG(2000) Succinyl is widely used in liposome preparation.

Application

DSPE-PEG(2000) succinyl has been used to prepare PEGylated liposomes, to obtain sterically stabilized liposomes containing docetaxel. It has also been used in liposomes for vasoactive intestinal peptide (VIP) encapsulation, to achieve PEGylation.
DSPE-PEG(2000) Succinyl has been used in micelle synthesis.

Packaging

5 mL Clear Glass Sealed Ampule (880121C-10mg)

RIDADR

UN 1888 6.1 / PGIII

Activating the Intrinsic Pathway of Apoptosis Using BIM BH3 Peptides Delivered by Peptide Amphiphiles with Endosomal Release
Schnorenberg MR, et al.
Materials, 12(16), 2567-2567 (2019)
Two cholesterol derivative-based PEGylated liposomes as drug delivery system, study on pharmacokinetics and drug delivery to retina
Geng S, et al.
Nanotechnology, 25(27), 275103-275103 (2014)
Preparation, characterization, cytotoxicity and pharmacokinetics of liposomes containing docetaxel
Immordino ML, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 91(3), 417-429 (2003)
Effects of poly (ethylene glycol)(PEG) concentration on the permeability of PEG-grafted liposomes
Hashizaki K, et al.
Chemical & Pharmaceutical Bulletin, 53(1), 27-31 (2005)
Mathew R Schnorenberg et al.
Materials (Basel, Switzerland), 12(16) (2019-08-15)
Therapeutic manipulation of the BCL-2 family using BH3 mimetics is an emerging paradigm in cancer treatment and immune modulation. For example, peptides mimicking the BIM BH3 helix can directly target the full complement of anti- and pro-apoptotic BCL-2 proteins to...

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