D-067

Supelco

洋地黄毒苷 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Empirical Formula (Hill Notation):
C41H64O13
CAS号:
分子量:
764.94
NACRES:
NA.24
价格与库存信息目前不能提供

Quality Level

grade

certified reference material

CofA

certificate is enclosed in each package

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

mfr. no.

Cerilliant®

concentration

1.0 mg/mL in methanol

Featured Industry

Pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

SMILES string

CC1OC(CC(O)C1O)OC2C(O)CC(OC2C)OC3C(O)CC(OC3C)OC4CCC5(C)C(CCC6C5CCC7(C)C(CCC67O)C8=CC(=O)OC8)C4

InChI

1S/C41H64O13/c1-20-36(46)29(42)16-34(49-20)53-38-22(3)51-35(18-31(38)44)54-37-21(2)50-33(17-30(37)43)52-25-8-11-39(4)24(15-25)6-7-28-27(39)9-12-40(5)26(10-13-41(28,40)47)23-14-32(45)48-19-23/h14,20-22,24-31,33-38,42-44,46-47H,6-13,15-19H2,1-5H3

InChI key

WDJUZGPOPHTGOT-UHFFFAOYSA-N

General description

A cardiac glycoside and antiarrhythmic drug similar in structure and effect to digoxin. Digitoxin is monitored by clinical labs to ensure patients remain within the drug′s therapeutic range.

Legal Information

CERILLIANT is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Cerilliant Corporation

Signal Word

Danger

Hazard Codes

F,T

Risk Statement

11-23/24/25-39/23/24/25

Safety Statement

16-36/37-45

RIDADR

UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

An elderly man with atrial fibrillation and exacerbated diabetes.
Ketil Arne Espnes et al.
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 132(9), 1103-1105 (2012-05-23)
Hosam A Elbaz et al.
Toxicology and applied pharmacology, 258(1), 51-60 (2011-11-01)
Mechanisms of digitoxin-inhibited cell growth and induced apoptosis in human non-small cell lung cancer (NCI-H460) cells remain unclear. Understanding how digitoxin or derivate analogs induce their cytotoxic effect below therapeutically relevant concentrations will help in designing and developing novel, safer...
Ryan Matsuda et al.
Journal of chromatography. A, 1265, 114-122 (2012-10-25)
High-performance affinity chromatography (HPAC) was used to examine the changes in binding that occur for the sulfonylurea drug glibenclamide with human serum albumin (HSA) at various stages of glycation for HSA. Frontal analysis on columns containing normal HSA or glycated...
Arne Hønnås et al.
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 130(13), 1334-1336 (2010-07-03)
In 2007, new Norwegian guidelines suggested that serum concentrations of digitoxin should be in the interval 8 - 15 nmol/l, which is about 50 % lower than previous recommendations. We studied trends in dosing and serum concentrations of digitoxin in...
[EKG-changes with gastrointestinal disorder].
H Boenigk et al.
Deutsche medizinische Wochenschrift (1946), 136(20), 1053-1054 (2011-05-12)

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